RSS by TUMJ http://tumj.tums.ac.ir Tehran University Medical Journal (TUMJ), the first and the oldest monthly medical journal in iran. Published since 1942. en-us Tehran University of Medical Sciences Wed, 15 Oct 2008 14:20:31 +0300 http://tumj.tums.ac.ir medjournal@tums.ac.ir, Wed, 15 Oct 2008 10:23:56 +0300 http://tumj.tums.ac.ir/archive/vol66/no7/abstract-1.html There are limited published investigations about adherence to antiretroviral and its determinants. Many determinants influence on adherence to therapy. The effects of some determinants on adherence are controversial. More studies are needed to be fulfilled about adherence and its determinants to compile strategies. Key to the success of antiretroviral therapies is the ability and willingness of HIV-positive individuals to adhere to antiretroviral regimens. There are different definitions for full adherence. In the most studies, adherence is defined as taking ≥95% of prescribed medication. Adherence rate needs to be >95% to prevent virologic failure and for complete supper-ssion. >>>

]]> Wed, 15 Oct 2008 12:14:36 +0300 http://tumj.tums.ac.ir/archive/vol66/no7/abstract-2.html Paraquat is an herbicide produced and used prevalently worldwide. Studies have shown that lung fibrosis induced by paraquat can be prevented or delayed by certain antioxidants, iron chelating agents, melatonin, and, recently, blood pressure lowering drugs such as captopril. The protective effects of captopril on paraquat toxicity were studied using RT-PCR and immunohistochemistry to determine the gene and protein expression of p53 and Bcl-2 in lung tissue samples from rats treated with captopril before and after exposure to paraquat. >>>

]]> Wed, 15 Oct 2008 12:14:44 +0300 http://tumj.tums.ac.ir/archive/vol66/no7/abstract-3.html Glycoconjugates are a class of cell surface glycoproteins, the terminal sugars of which are important indicators of neoplasia and the aberrant biological behavior of cancer cells. Lectins are a class of plant or animal glycoproteins that specifically bind to the terminal sugars of glycoconjugates. The aim of the present study is to identify the presence of L-fucose in cell surface glycoconjugates and extracellular matrix glycoconjugates of cancer cells of different grades of colonic adenocarcinoma. Paraffin blocks of colonic adenocarcinoma tissue from 30 patients were collected from the Pathology Department of Khatam Al Anbia Hospital in Zahedan, Iran. >>>

]]> Wed, 15 Oct 2008 12:14:50 +0300 http://tumj.tums.ac.ir/archive/vol66/no7/abstract-4.html Chronic peritoneal dialysis is a safe method for the treatment of end-stage renal failure. Worldwide, patients on chronic peritoneal dialysis constititute approximately 15% of the total number of patients on dialysis. In Iran, very few people have access to chronic peritoneal dialysis, which is targeted by the Ministry of Health. This lack of access is primarily due to the high occurrence of mechanical complications. Improving catheterization procedures is an important way to extend the use of peritoneal dialysis in Iran. >>>

]]> Wed, 15 Oct 2008 12:14:59 +0300 http://tumj.tums.ac.ir/archive/vol66/no7/abstract-5.html Approximately 2-15% of the global population suffers from migraine headaches. Since acupuncture is one of the treatments for this disorder, the aim of the present study was to assess the effectiveness of this modality on patients with migraine. In this experimental interventional study, we enrolled 180 patients with migraine headache attacks at a documented frequency of at least 2 attacks during last 6 months. For all patients, the number, duration and intensity of the headaches were recorded before treatment. To treat the patients, the point with maximal pain was first determined and the meridian was distinguished. >>>

]]> Wed, 15 Oct 2008 12:15:06 +0300 http://tumj.tums.ac.ir/archive/vol66/no7/abstract-6.html Ovarian cancer is the leading cause of death among all gynecologic cancers in developed countries. The standard treatment for advanced ovarian cancer consists of cytoreductive surgery associated with a platinum/paclitaxel-based chemotherapy. Over than 50% of patients with advanced ovarian cancer will develop recurrent disease. For those patients who have recurrence of disease at least six months after initial therapy, the paclitaxel- platinum combination has been shown to be a superior treatment to platinum monotherapy. However, many patients develop clinically relevant neurotoxicity, frequently resulting in treatment discontinuation. >>>

]]> Wed, 15 Oct 2008 12:15:15 +0300 http://tumj.tums.ac.ir/archive/vol66/no7/abstract-7.html Chlamydia trachomatis is a common and curable STI that may be symptomatic or asymptomatic. The few studies on C. trachomatis among Iranian women have had, for the most part, small sample sizes and are therefore unsuitable for epidemiological deductions. The aim of this study was to estimate the prevalence of urogenital C. trachomatis infections by PCR on urine samples of married women in their fertile years in order to determine the need for a C. trachomatis screening program for asymptomatic women in Iran. >>>

]]> Wed, 15 Oct 2008 12:15:23 +0300 http://tumj.tums.ac.ir/archive/vol66/no7/abstract-8.html Cyclosporine is one of the main immunosuppressors used for renal transplant recipients, and is given to prevent transplant rejection. Although the drug increases the survival of patients and grafted organs, it has some side effects independent of its effect on the immune system that are usually ignored. In this study, we evaluate the effect of cyclosporine on serum Mg levels and metabolic side effects in renal graft patients. In this study, we followed 157 renal transplant recipients (62 females and 95 males) who were being treated with cyclosporine at a private clinic to >>>

]]> Wed, 15 Oct 2008 12:15:38 +0300 http://tumj.tums.ac.ir/archive/vol66/no7/abstract-9.html The preferred modality of dialysis is a controversial issue in nephrology. In this study we compare some demographic and epidemiological characteristics of hemodialysis and peritoneal dialysis patients in an attempt to analyze this issue. The results of the research protocol “A survey of the epidemiological characteristics of chronic dialyzed patients in Khorassan province”, was used to compare some demographic and epidemiological aspects of chronic hemodialysis and peritoneal dialysis patients in search of any statistically significant difference. A total of 836 chronic dialysis patients entered this study, 802 (95.9%) of which were under chronic hemodialysis, and 34 (4.1%) patients were undergoing peritoneal >>>

]]> Wed, 15 Oct 2008 12:15:48 +0300 http://tumj.tums.ac.ir/archive/vol66/no7/abstract-10.html Atherosclerosis and the side effects thereof are a major cause of mortality and morbidity in diabetic patients. Diabetic dyslipidemia is defined by a decrease in blood levels of HDL cholesterol and increases in triglycerides and LDL cholesterol. Diabetic dyslipidemia is atherogenic, inducing cardiovascular disease in diabetic patients at a frequency that is two to three times greater than that of nondiabetics. This study analyzes the data from the first phase of the Yazd Healthy Heart Program, a community intervention project focused on the prevention of cardiovascular disease. Using the cluster sampling method, we analyzed data from 2000 subjects from Yazd, Iran, ranging in age from 20 to 74 years. >>>

]]> Wed, 15 Oct 2008 12:15:56 +0300 http://tumj.tums.ac.ir/archive/vol66/no7/abstract-11.html Infertility influences various aspects of a woman’s personality and psyche, and affects her functions within her family and occupation, as well as her ability to communicate. Studies have shown that infertility is associated with depression, stress, anxiety, dissatisfaction with life and other psychological problems. The purpose of the present study was to compare the dimensions of neuroticism and androgyny in fertile, infertile and postmenopausal women. This study included of 180 fertile, infertile and postmenopausal women (60 in each group) selected from inpatients at Imam Khomeini and Mirza Koochak Khan Hospitals, Tehran, Iran, during 2004. >>>

]]> Wed, 15 Oct 2008 12:16:06 +0300 http://tumj.tums.ac.ir/archive/vol66/no7/abstract-12.html A high percentage of the patients at ENT or plastic surgery clinics have ENT abnormalities, either congenital or those developing later in life. Some are life threatening, while others cause disability and esthetic problems, with profound consequences for the affected child and the family. In addition, ENT abnormalities usually place stress on interpersonal relationships, causing social isolation, unhappiness and depression. The majority of these abnormalities is genetic and follows autosomal recessive pattern of inheritance. Geneticists believe that there is a higher frequency of autosomal recessive disorders among the offspring of consanguineous parents. >>>

]]> Wed, 15 Oct 2008 12:16:14 +0300 http://tumj.tums.ac.ir/archive/vol66/no7/abstract-13.html Lead poisoning could be associated with gastrointestinal renal, hematologic complications and neurologic deficit. The patient was an opium addict, forty one years old male, to hospital admitted with gastrointestinal signs, constipation, abdominal pain, severe weakness of upper and lower limbs without any sensory impairment and with anemia, leukocytosis, and slightly increased liver function tests. Serum level of lead was more than 200µg/dl. After treatment with dimercaprol (BAL), CaNa2EDTA for two five days sessions that followed with oral succimer for three days, signs and symptoms relieved, all laboratory tests became normal and blood level of lead reduced but the patient was >>>

]]> Wed, 15 Oct 2008 12:16:24 +0300 http://tumj.tums.ac.ir/archive/vol66/no7/abstract-14.html Port-site metastasis following laparoscopic cholecystectomy with unsuspected gallbladder carcinoma is a serious problem. Gallbladder carcinoma is found in 1% of all biliary tract operations, in most being diagnosed only after histological examination of the gallbladder. The spread of cancer following laparoscopy appears aggressive and widespread, as noticed from re-operation for radical treatment. The pathologic findings of gallbladder were consisting of tumoral and necrotic tissue, indicating of well differentiated adenocarcinoma. Mucosa and submucosa were involved, but no evidence of invasion to muscular layer and gall bladder serosa was found (T1). >>>

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