Volume 60, Issue 5 (15 2002)                   Tehran Univ Med J 2002, 60(5): 371-377 | Back to browse issues page

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Abstract:   (4930 Views)
This study was conducted to show the comparison of efficacy and survival of amniotic membrane grafts and homologous dura grafts.
Methods and Materials: In this study, ten dogs (age 6-9 months & weight 15 lo 20 kg) have been chosen. The study was a single blind clinical trial. The dogs have been assigned into two groups by random allocation method. The amniotic membrane (A.M) was taken from a placenta belonging to a 38 weeks fetus delivered in a cesarean section surgery. In one group the graft was a peace of dura mater and in the other one the graft was a homologous dura graft. Maintenance of all cases was the same. Forty-five days later, another surgeon who was not aware of the assignment, conducted the second exploratory surgery for evaluation of the results.
Results: None of cases in two groups had any infection, abscess formation, fistula, CSF leakage or any toxic status. The healing process was normal in both groups.
Conclusion: There seems to be no difference between the (A.M) grafts and homologous dura in the repairmen of dura mater. This is expected to occur only if the pregnant woman is carefully tested for the presence of certain clinical conditions and the preparation of A.M is contemplated in an ideal environment.
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