Volume 60, Issue 5 (15 2002)                   Tehran Univ Med J 2002, 60(5): 378-382 | Back to browse issues page

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Hajy Mohammadi F, Fard F, Taheri A, Hoozan B. Clonidine Reduce Bleeding Of Endoscopic Sinus Surgery Amir Alam Hospital (1398-2000). Tehran Univ Med J. 2002; 60 (5) :378-382
URL: http://tumj.tums.ac.ir/article-1-1230-en.html
Abstract:   (3786 Views)
This study was conducted to evaluate effect of clonidine as a premedication on endoscopic sinus surgery bleeding.
Methods and Materials: during a randomized double blind clinical trial we compared two groups of patients who scheduled for endoscopic sinus surgery for polypectomy and etmoidectomy. 216 patients randomly assigned in two groups.In first group 2 hours befor surgery a 0.2mg tablet of clonidine orally adminestered to patients and in second group a 100 mg tablet of vit Bj(with same size and color- as
placebo)was adminestered to patients. The amount of bleeding measured in two groups.
Results: mean bleeding volume in clonidine group was 113+76 ml and in control group was 211 + 113 ml. There was a significant statistical difference between two groups (pO.0001).
Conclusion: Clonidine as premedication can reduce bleeding of endoscopic sinus surgery significantly.
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