Volume 58, Issue 2 (7 2000)                   Tehran Univ Med J 2000, 58(2): 49-55 | Back to browse issues page

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Sobhani A, Radmehr B, Raji AR. Gross anatomic and radiographic study of bone matrix gelatin implantation in tibial fracture of rabbit1. Tehran Univ Med J. 2000; 58 (2) :49-55
URL: http://tumj.tums.ac.ir/article-1-1408-en.html
Abstract:   (3720 Views)
Different ossificant materials have been used for induction of bone repair in many studies, and bone matrix gelatin which contains bone morphogenic proteins is one of the best ones. In present study we evaluated the role of this material in acceleration of bone repair in rabbit tibia. A hole of 3.5 mm diameter was made on right tibia of 10 and 12 rabbits as study and control group respectively. In the experiment group, in addition to Bone Wax, we applied bone matrix gelatin in the hole. Radiographic images were taken in days 0, 20, 40 and 53 after operation. In 6 rabbits of each group, photographic pictures were also taken after exposure of entire bone. In 6 controls less degree of restoration were seen on day 53. In 4 experimental animals restoration were completed by this time and in 2 speciments repair processing were better than controls. This results shows that bone matrix gelatin can be used as a accelerator of bone repair.
Keywords: Ossification
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