Volume 56, Issue 2 (30 1998)                   Tehran Univ Med J 1998, 56(2): 35-37 | Back to browse issues page

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Abstract:   (20528 Views)
Griseofulvin is a well-known, effective, systemic antifungal agent which has not been used topically in the current clinical practice. In order to treat the common superficial fungal infection of tinea versicolor, a new topical formulation of griseofulvin (1%) was tried in 105 patients during a double blind study and its efficacy compared with placebo (its vehicle) and clotrimazol (1%) solutions. As a result, 17.9% of patients treated by griseofulvin, 38.9% of patients on clotrimazole and 3.3% of patients receiving placebo were completely cured. This study suggests that in proper solvent, topical griseofulvin might show its antifungal action.
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