Volume 69, Issue 3 (5 2011)                   Tehran Univ Med J 2011, 69(3): 204-209 | Back to browse issues page

XML Persian Abstract Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

N B, A R, A Z, M J. The acute effects of strength training on inflammatory markers predicting atherosclerosis: a study on inactive middle-aged men. Tehran Univ Med J. 2011; 69 (3) :204-209
URL: http://tumj.tums.ac.ir/article-1-258-en.html
1- , bijeh@um.ac.ir
Abstract:   (4767 Views)
Background: Cardiovascular diseases, especially atherosclerosis, are the main causes of morbidity and mortality worldwide. The disease has had an increasing prevalence in Iran in recent years. Homocysteine and C-reactive protein (CRP) are two novel cardiovascular risk factors that independently predict risks of atherosclerosis. The purpose of this study was to investigate the effects of one session of circuit resistance training on the blood levels of the aforesaid inflammatory markers in inactive middle- aged men. Methods: The participants of this study included twenty-three healthy but inactive middle-aged men who were overweight and were randomly divided into two experimental (n=14) and control (n=9) groups. The activity included doing exercises with the subjects’ 35% one-repetition maximum (1-RM) intensity at ten different stations. Blood levels of homocysteine and hs-CRP were measured before and after the exercise. Results: Analysis of data using independent samples t-test showed a significant increment in the serum levels of homocysteine and hs-CRP after training in the experimental (P<0.05) versus the control group. Conclusion: Elevation of homocysteine levels is due to the increase in protein metabolism and creatine synthesis for energy production and elevation of hs-CRP levels could be due to hepatic induction of interleukin-6 that acts as a signal for the stimulation of lipolysis and glycogenolysis. However, beneficial or adverse physiological effects of these changes are not thoroughly understood and more research is needed to conclude about the acute and chronic effects of different types of physical activity on the blood levels of these atherosclerosis risk factors.
Full-Text [PDF 274 kb]   (1302 Downloads)    

Add your comments about this article : Your username or Email:
CAPTCHA

Send email to the article author


© 2019 All Rights Reserved | Tehran University Medical Journal TUMS Publications

Designed & Developed by : Yektaweb