Volume 56, Issue 1 (30 1998)                   Tehran Univ Med J 1998, 56(1): 26-29 | Back to browse issues page

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Keshavarz A, Jalali M, Ebrahimi Mamaghani M. Microcytic Anemia in Children with Phenylketonuria in Tehran. Tehran Univ Med J 1998; 56 (1) :26-29
URL: http://tumj.tums.ac.ir/article-1-1589-en.html
Abstract:   (6607 Views)
Sixty-nine children with phenylketonuria (PKU) under coverage of Tehran Genetic Research and
Consultation Center, fed Lofenalac and Phenylfree were studied. The 24-hour dietary recall method was used
to determine food intake and blood samples were analyzed for iron parameters. The results showed that over
7% of the children had a low intake of energy, protein and iron. In addition, hemoglobin and hematocrit were
lower than normal in 3.1% of the children, while in 24.2% of them there was decreased serum transferrin
saturation percent. There was a statistically significant relationship between lenght of diet therapy and iron
parameters. The findings show that inadequate nutrient intakes may, over time, cause appearance of anemia signs in the children with PKU dependent on special formulations
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