Volume 68, Issue 12 (6 2011)                   Tehran Univ Med J 2011, 68(12): 749-752 | Back to browse issues page

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AH E, P N, S J, H G. An unusual presentation of pruritic urticarial Papules and Plaques of Pregnancy: a case report. Tehran Univ Med J 2011; 68 (12) :749-752
URL: http://tumj.tums.ac.ir/article-1-288-en.html
1- , normohamad@razi.tums.ac.ir
Abstract:   (5607 Views)
Background: Pruritic Urticarial Papules and Plaques of Pregnancy (PUPPP) is a specific dermatosis of the third trimester of pregnancy, commonly seen in primigravid women.
Case presentation: A 24-year-old primigravida woman who had developed a rash immediately after delivery was admitted to Razi Hospital in Tehran, Iran. She had an erythematous eruption, particularly concentrated on the abdominal striae with umbilical sparing and involvement of limbs and extremities. Skin biopsy of the lesions on the lower abdomen, showed superficial perivascular infiltrates with occasional neutrophils and eosinophils. Both direct and indirect immunofloresence assays were negative. The patient was ultimately treated with topical clobetasol butyrate and oral chlorpheniramine for pruritus. Within a week, the lesions and the itchings had disappeared completely.
Conclusion: Pruritic urticarial papules and plaques of pregnancy are often, but not always, seen during the third trimester of pregnancy, but sometimes they present in postpartum period without any prior manifestations during pregnancy.

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