Volume 71, Issue 9 (December 2013)                   Tehran Univ Med J 2013, 71(9): 603-608 | Back to browse issues page

XML Persian Abstract Print

Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Daryanoosh F, Jafari H, Rahimi E, Mehrbani D, Soltani F. The effect of eight week interval acute training on plasma visfatin, TNF-α and IL-6 in rats: a brief report. Tehran Univ Med J 2013; 71 (9) :603-608
URL: http://tumj.tums.ac.ir/article-1-5687-en.html
1- Department of Physical Education, Faculty of Education and Psychology, Shiraz University, Shiraz, Iran.
2- Department of Exercise Physiology, Shiraz University, Shiraz, Iran. , physio.shirazu@yahoo.com
3- Department of Physical Education, Islamic Azad University of Shiraz, Shiraz, Iran.
4- Shiraz University of Medical Science, Shiraz, Iran.
5- Department of Exercise Physiology, Shiraz University, Shiraz, Iran.
Abstract:   (11931 Views)
Background: Adipokines are peptides secreted by adipose tissue that affect whole-body energy metabolism. Exercise training exerts beneficial effects on adipose tissue. However, less is known regarding visfatin’s, IL-6 & TNF-α response to an interval acute training. Therefore, we investigated the effects of acute interval exercise on plasma visfatin, TNF-α and IL-6 levels, in healthy female rats. Furthermore, correlate between changes probably these factors were also assessed.
Methods: This study was conducted experimentally. Forty five female sprague dawley rat were randomly divided into three groups: pre test (n= 15), treadmill exercise (n= 15) and sedentary controls (n= 15). The acute alternative exercise consisted of treadmill running: 3 session/ week for 8 week. The changes of plasma IL-6, TNF-α and Visfatin levels were measured by ELISA analysis. Data were analyzed using analysis of variance with measures (ANOVA) and post hoc Tukey test.
Results: Acute interval treadmill exercise led to significant decreases in visfatin (P= 0/036), IL-6 (P= 0/009) and TNF-α (P= 0/022) plasma levels between the groups. Also, this study no significant correlations between the changes in adipokines were observed.
Conclusion: Decreased levels of TNF-α and IL-6 correlated with intensity and duration exercise. Furthermore, probably there were some factors except weight decreasing that affects on visfatin decrease. Therefore, the reduction of this factor may cause in preventing metabolic disease.
Full-Text [PDF 431 kb]   (3075 Downloads)    
Type of Study: Brief Report |

Add your comments about this article : Your username or Email:

Send email to the article author

Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

© 2023 , Tehran University of Medical Sciences, CC BY-NC 4.0

Designed & Developed by : Yektaweb