<?xml version="1.0" encoding="utf-8"?>
<journal>
<title>Tehran University Medical Journal</title>
<title_fa>مجله دانشکده پزشکی، دانشگاه علوم پزشکی تهران</title_fa>
<short_title>Tehran Univ Med J</short_title>
<subject>Medical Sciences</subject>
<web_url>http://tumj.tums.ac.ir</web_url>
<journal_hbi_system_id>1</journal_hbi_system_id>
<journal_hbi_system_user>admin</journal_hbi_system_user>
<journal_id_issn>1683-1764</journal_id_issn>
<journal_id_issn_online>1735-7322</journal_id_issn_online>
<journal_id_pii></journal_id_pii>
<journal_id_doi>10.18869/acadpub.tumj</journal_id_doi>
<journal_id_iranmedex></journal_id_iranmedex>
<journal_id_magiran></journal_id_magiran>
<journal_id_sid>000</journal_id_sid>
<journal_id_nlai>000</journal_id_nlai>
<journal_id_science>000</journal_id_science>
<language>fa</language>
<pubdate>
	<type>jalali</type>
	<year>1391</year>
	<month>3</month>
	<day>1</day>
</pubdate>
<pubdate>
	<type>gregorian</type>
	<year>2012</year>
	<month>6</month>
	<day>1</day>
</pubdate>
<volume>70</volume>
<number>3</number>
<publish_type>online</publish_type>
<publish_edition>1</publish_edition>
<article_type>fulltext</article_type>
<articleset>
	<article>


	<language>fa</language>
	<article_id_doi></article_id_doi>
	<title_fa>مقایسه اندازه ضخامت جدار اینتیما- مدیا شریان کاروتید در دیابتی‌های تیپ 2 مبتلا به رتینوپاتی و بدون رتینوپاتی</title_fa>
	<title>Comparing carotid intima-media thickness in type 2 diabetes between patients with and without retinopathy</title>
	<subject_fa></subject_fa>
	<subject></subject>
	<content_type_fa></content_type_fa>
	<content_type></content_type>
	<abstract_fa>&lt;p dir=&quot;rtl&quot; style=&quot;text-align: justify&quot;&gt;&lt;o:officedocumentsettings&gt; &lt;o:targetscreensize&gt;800x600&lt;/o:targetscreensize&gt; &lt;/o:officedocumentsettings&gt; &lt;w:view&gt;Normal&lt;/w:view&gt; &lt;w:zoom&gt;0&lt;/w:zoom&gt; &lt;w:trackmoves&gt; &lt;w:trackformatting&gt; &lt;w:punctuationkerning&gt; &lt;w:validateagainstschemas&gt; &lt;w:saveifxmlinvalid&gt;false&lt;/w:saveifxmlinvalid&gt; &lt;w:ignoremixedcontent&gt;false&lt;/w:ignoremixedcontent&gt; &lt;w:alwaysshowplaceholdertext&gt;false&lt;/w:alwaysshowplaceholdertext&gt; &lt;w:donotpromoteqf&gt; &lt;w:lidthemeother&gt;EN-US&lt;/w:lidthemeother&gt; &lt;w:lidthemeasian&gt;X-NONE&lt;/w:lidthemeasian&gt; &lt;w:lidthemecomplexscript&gt;AR-SA&lt;/w:lidthemecomplexscript&gt; &lt;w:compatibility&gt; &lt;w:breakwrappedtables&gt; &lt;w:snaptogridincell&gt; &lt;w:wraptextwithpunct&gt; &lt;w:useasianbreakrules&gt; &lt;w:dontgrowautofit&gt; &lt;w:splitpgbreakandparamark&gt; &lt;w:enableopentypekerning&gt; &lt;w:dontflipmirrorindents&gt; &lt;w:overridetablestylehps&gt; &lt;/w:overridetablestylehps&gt;&lt;/w:dontflipmirrorindents&gt;&lt;/w:enableopentypekerning&gt;&lt;/w:splitpgbreakandparamark&gt;&lt;/w:dontgrowautofit&gt;&lt;/w:useasianbreakrules&gt;&lt;/w:wraptextwithpunct&gt;&lt;/w:snaptogridincell&gt;&lt;/w:breakwrappedtables&gt;&lt;/w:compatibility&gt; &lt;w:browserlevel&gt;MicrosoftInternetExplorer4&lt;/w:browserlevel&gt; &lt;m:mathpr&gt; &lt;m:mathfont m:val=&quot;Cambria Math&quot;&gt; &lt;m:brkbin m:val=&quot;before&quot;&gt; &lt;m:brkbinsub m:val=&quot;--&quot;&gt; &lt;m:smallfrac m:val=&quot;off&quot;&gt; &lt;m:dispdef&gt; &lt;m:lmargin m:val=&quot;0&quot;&gt; &lt;m:rmargin m:val=&quot;0&quot;&gt; &lt;m:defjc m:val=&quot;centerGroup&quot;&gt; &lt;m:wrapindent m:val=&quot;1440&quot;&gt; &lt;m:intlim m:val=&quot;subSup&quot;&gt; &lt;m:narylim m:val=&quot;undOvr&quot;&gt; &lt;/m:narylim&gt;&lt;/m:intlim&gt;&lt;/m:wrapindent&gt;&lt;/m:defjc&gt;&lt;/m:rmargin&gt;&lt;/m:lmargin&gt;&lt;/m:dispdef&gt;&lt;/m:smallfrac&gt;&lt;/m:brkbinsub&gt;&lt;/m:brkbin&gt;&lt;/m:mathfont&gt;&lt;/m:mathpr&gt; 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semihidden=&quot;false&quot; unhidewhenused=&quot;false&quot;&gt; &lt;w:lsdexception locked=&quot;false&quot; name=&quot;Medium Grid 1 Accent 4&quot; priority=&quot;67&quot; semihidden=&quot;false&quot; unhidewhenused=&quot;false&quot;&gt; &lt;w:lsdexception locked=&quot;false&quot; name=&quot;Medium Grid 2 Accent 4&quot; priority=&quot;68&quot; semihidden=&quot;false&quot; unhidewhenused=&quot;false&quot;&gt; &lt;w:lsdexception locked=&quot;false&quot; name=&quot;Medium Grid 3 Accent 4&quot; priority=&quot;69&quot; semihidden=&quot;false&quot; unhidewhenused=&quot;false&quot;&gt; &lt;w:lsdexception locked=&quot;false&quot; name=&quot;Dark List Accent 4&quot; priority=&quot;70&quot; semihidden=&quot;false&quot; unhidewhenused=&quot;false&quot;&gt; &lt;w:lsdexception locked=&quot;false&quot; name=&quot;Colorful Shading Accent 4&quot; priority=&quot;71&quot; semihidden=&quot;false&quot; unhidewhenused=&quot;false&quot;&gt; &lt;w:lsdexception locked=&quot;false&quot; name=&quot;Colorful List Accent 4&quot; 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&lt;strong&gt;&lt;span style=&quot;font-size: 10pt&quot;&gt;زمینه و هدف:&lt;/span&gt;&lt;em&gt;&lt;span style=&quot;font-size: 10pt&quot;&gt;&amp;nbsp;&lt;/span&gt;&lt;/em&gt;&lt;/strong&gt;&lt;span style=&quot;font-size: 10pt&quot;&gt;بیماری&#8204;های میکروواسکولار و ماکروواسکولار در زمینه بیماری دیابت تیپ دو از مدت&#8204;ها قبل شناخته شده&#8204;اند. &lt;span style=&quot;color: black&quot;&gt;هر دو نوع درگیری شریان،&lt;/span&gt; دارای ریسک فاکتور کم و بیش مشابهی هستند و &lt;span style=&quot;color: black&quot;&gt;با دیابت همراهی دارند، &lt;/span&gt;لیکن مطالعات زیادی در خصوص همراهی درگیری واسکولار شبکیه با درگیری عروق بزرگ نظیر کاروتید در مبتلایان به دیابت تیپ دو انجام نشده است. در این مطالعه سعی شده است تا ارتباط درگیری میکروواسکولار شبکیه با ضخامت لایه اینتیما- مدیا کاروتید بررسی شود.&lt;/span&gt;&lt;span style=&quot;font-size: 9pt&quot;&gt;&amp;nbsp;&lt;/span&gt;&lt;/w:donotpromoteqf&gt;&lt;/w:validateagainstschemas&gt;&lt;/w:punctuationkerning&gt;&lt;/w:trackformatting&gt;&lt;/w:trackmoves&gt;&lt;/p&gt;

&lt;p dir=&quot;rtl&quot; style=&quot;text-align: justify&quot;&gt;&lt;strong&gt;&lt;span style=&quot;font-size: 10pt&quot;&gt;روش بررسی:&lt;/span&gt;&lt;em&gt;&lt;span style=&quot;font-size: 10pt&quot;&gt;&amp;nbsp;&lt;/span&gt;&lt;/em&gt;&lt;/strong&gt;&lt;span style=&quot;font-size: 10pt&quot;&gt;در این مطالعه به&#8204;روش مورد- شاهدی تعداد 100 بیمار مبتلا به دیابت نوع دو بررسی شدند. ضخامت لایه اینتیما و مدیای شریان کاروتید با استفاده از سونوگرافی داپلر رنگی اندازه&#8204;گیری شد و با نتایج به&#8204;دست&#8204;آمده از معاینات چشم&#8204;پزشکی مقایسه گردید.&lt;strong&gt;&amp;nbsp;&lt;/strong&gt;&lt;/span&gt;&lt;/p&gt;

&lt;p dir=&quot;rtl&quot; style=&quot;text-align: justify&quot;&gt;&lt;strong&gt;&lt;span style=&quot;font-size: 10pt&quot;&gt;یافته&#8204;ها:&lt;/span&gt;&lt;/strong&gt;&lt;span style=&quot;font-size: 10pt&quot;&gt;&amp;nbsp;&lt;/span&gt;&lt;span style=&quot;font-size: 10pt&quot;&gt;رتینوپاتی دیابتی در 50 بیمار (50%) وجود داشت. ضخامت لایه اینتیما- مدیا در این بیماران در مقایسه با بیماران فاقد رتینوپاتی بیش&#8204;تر بود (17/0&lt;/span&gt;&lt;span style=&quot;font-size: 8pt&quot;&gt;&amp;plusmn;&lt;/span&gt;&lt;span style=&quot;font-size: 10pt&quot;&gt;77/0 در برابر 2/0&lt;/span&gt;&lt;span style=&quot;font-size: 8pt&quot;&gt;&amp;plusmn;&lt;/span&gt;&lt;span style=&quot;font-size: 10pt&quot;&gt;71/0 میلی&#8204;متر 041/0&lt;/span&gt;&lt;span style=&quot;font-size: 7pt&quot;&gt;P=&lt;/span&gt;&lt;span style=&quot;font-size: 10pt&quot;&gt;). هم&#8204;چنین در بیماران دچار رتینوپاتی پرولیفراتیو در مقابل نان- پرولیفراتیو بیش&#8204;تر بود (&lt;/span&gt;&lt;span style=&quot;font-size: 10pt&quot;&gt;16/0&lt;/span&gt;&lt;span style=&quot;font-size: 8pt&quot;&gt;&amp;plusmn;&lt;/span&gt;&lt;span style=&quot;font-size: 10pt&quot;&gt;87/0&lt;/span&gt;&lt;span style=&quot;font-size: 10pt&quot;&gt; در برابر &lt;/span&gt;&lt;span style=&quot;font-size: 10pt&quot;&gt;10/0&lt;/span&gt;&lt;span style=&quot;font-size: 8pt&quot;&gt;&amp;plusmn;&lt;/span&gt;&lt;span style=&quot;font-size: 10pt&quot;&gt;68/0&lt;/span&gt;&lt;span style=&quot;font-size: 10pt&quot;&gt;&amp;nbsp;&lt;/span&gt;&lt;span style=&quot;font-size: 10pt&quot;&gt;میلی&#8204;متر 001/0&lt;/span&gt;&lt;span style=&quot;font-size: 7pt&quot;&gt;P&lt;&lt;/span&gt;&lt;span style=&quot;font-size: 10pt&quot;&gt;).&lt;/span&gt;&lt;strong&gt;&lt;em&gt;&lt;span style=&quot;font-size: 10pt&quot;&gt; &lt;/span&gt;&lt;/em&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p dir=&quot;rtl&quot; style=&quot;text-align: justify&quot;&gt;&lt;strong&gt;&lt;span style=&quot;font-size: 10pt&quot;&gt;نتیجه&#8204;گیری:&lt;/span&gt;&lt;em&gt;&lt;span style=&quot;font-size: 10pt&quot;&gt;&amp;nbsp;&lt;/span&gt;&lt;/em&gt;&lt;/strong&gt;&lt;span style=&quot;font-size: 10pt&quot;&gt;میان رتینوپاتی دیابتی با افزایش ضخامت لایه اینتیما- مدیا و درگیری کاروتید همراهی وجود دارد و وجود یکی از این یافته&#8204;ها می&#8204;تواند نشان&#8204;دهنده وجود عارضه دیگر باشد. پیشنهاد می&#8204;گردد که در بیماران دیابتی که به&#8204;صورت روتین تحت معاینات چشم&#8204;پزشکی قرار می&#8204;گیرند، با مشاهده رتینوپاتی دیابتی، به&#8204;خصوص رتینوپاتی پرولیفراتیو وضعیت عروق کاروتید با استفاده از روش&#8204;های غیر&#8204;تهاجمی نظیر سونوگرافی کالر داپلر به&#8204;منظور تشخیص بیماری&#8204;های شریان کاروتید و پیشگیری از حوادث عروق مغزی بررسی گردد.&lt;/span&gt;&lt;/p&gt;
</abstract_fa>
	<abstract>&lt;p style=&quot;text-align: justify&quot;&gt;&lt;strong&gt;Background&lt;/strong&gt;: Microangiopathy and macroangiopathy frequently coexist in type 2 diabetes mellitus (T2DM). Both types of the vascular complications share traditional risk factors but it is not clear whether the presence of microangiopathy, such as diabetic retinopathy, constitutes a predictor of atherosclerosis in carotid arteries in patients with the disease. In this study we looked for the association between diabetic retinopathy and intima-media thickness in carotid arteries of patients with T2DM.&lt;/p&gt;

&lt;p style=&quot;text-align: justify&quot;&gt;&lt;strong&gt;Methods&lt;/strong&gt;: In this case-control study we examined 100 consecutive patients with T2DM in Rasoul Akram Hospital in Tehran, Iran during 2009-2010. We assessed intima-media thickness of carotid arteries by ultrasonography. All patients underwent ophthalmo-logic examination.&lt;/p&gt;

&lt;p style=&quot;text-align: justify&quot;&gt;&lt;strong&gt;Results&lt;/strong&gt;: Diabetic retinopathy was found in 50 (50%) patients. Intima-media thickness was higher in patients with diabetic retinopathy than those without it (0.77&amp;plusmn;0.17 mm vs. 0.71&amp;plusmn;0.2 mm, respectively, P=0.041). Moreover, intima-media thickness was more prevalent in patients with proliferative diabetic retinopathy than patients with non-proliferative form of the disease (0.87&amp;plusmn;0.16 mm vs. 0.68&amp;plusmn;0.1 mm, respectively, P&lt;0.001).&lt;/p&gt;

&lt;p style=&quot;text-align: justify&quot;&gt;&lt;strong&gt;Conclusion&lt;/strong&gt;: Diabetic retinopathy seems to be associated with increased intima-media thickness of carotid arteries in T2DM. It may be a common denominator of pathogene-sis of microvascular complications and atherosclerosis in T2DM. Evaluations of carotid arteries are to be done by non-invasive methods such as color Doppler sonography for screening and preventing prospective cereberovascular accidents in patients with diabetic retinopathy, especially proliferative retinopathy, in routine ophthalmological examination of patients with T2DM.&lt;/p&gt;
</abstract>
	<keyword_fa>دیابت,رتینوپاتی,کاروتید,ضخامت لایه اینتیما, مدیا</keyword_fa>
	<keyword>Carotid intima-media thickness,diabetes,retinopathy</keyword>
	<start_page>150</start_page>
	<end_page>155</end_page>
	<web_url>http://tumj.tums.ac.ir/browse.php?a_code=A-10-3758-2&amp;slc_lang=fa&amp;sid=1</web_url>


<author_list>
	<author>
	<first_name>Naroi Nejad</first_name>
	<middle_name></middle_name>
	<last_name>Minoo </last_name>
	<suffix></suffix>
	<first_name_fa>مینو</first_name_fa>
	<middle_name_fa></middle_name_fa>
	<last_name_fa>نارویی‌نژاد</last_name_fa>
	<suffix_fa></suffix_fa>
	<email></email>
	<code></code>
	<orcid></orcid>
	<coreauthor>No</coreauthor>
	<affiliation>Department of Radiology, Rasoul Hospital, Faculty of Medicine, Tehran University of Medical Sciences, Tehran, Iran</affiliation>
	<affiliation_fa>دانشکده پزشکی، بیمارستان حضرت رسول اکرم ،دانشگاه علوم پزشکی تهران، تهران، ایران.</affiliation_fa>
	 </author>


	<author>
	<first_name>Yousefi</first_name>
	<middle_name></middle_name>
	<last_name>Maryam</last_name>
	<suffix></suffix>
	<first_name_fa>مریم</first_name_fa>
	<middle_name_fa></middle_name_fa>
	<last_name_fa>یوسفی</last_name_fa>
	<suffix_fa></suffix_fa>
	<email>yousefimaryam77@yahoo.com</email>
	<code></code>
	<orcid></orcid>
	<coreauthor>Yes
</coreauthor>
	<affiliation>Department of Radiology, Rasoul Hospital, Faculty of Medicine, Tehran University of Medical Sciences, Tehran, Iran</affiliation>
	<affiliation_fa>دانشکده پزشکی، بیمارستان حضرت رسول اکرم، دانشگاه علوم پزشکی تهران، تهران، ایران.</affiliation_fa>
	 </author>


	<author>
	<first_name>Nazari</first_name>
	<middle_name></middle_name>
	<last_name>Hossein</last_name>
	<suffix></suffix>
	<first_name_fa>حسین</first_name_fa>
	<middle_name_fa></middle_name_fa>
	<last_name_fa>نظری</last_name_fa>
	<suffix_fa></suffix_fa>
	<email></email>
	<code></code>
	<orcid></orcid>
	<coreauthor>No</coreauthor>
	<affiliation>Department of Ophthalmology, Rasoul Hospital, Faculty of Medicine, Tehran University of Medical Sciences, Tehran, Iran</affiliation>
	<affiliation_fa>دانشکده پزشکی، بیمارستان حضرت رسول اکرم ،دانشگاه علوم پزشکی تهران، تهران، ایران.</affiliation_fa>
	 </author>


	<author>
	<first_name>Ghasempoor</first_name>
	<middle_name></middle_name>
	<last_name>Adel</last_name>
	<suffix></suffix>
	<first_name_fa>عادل</first_name_fa>
	<middle_name_fa></middle_name_fa>
	<last_name_fa>قاسم‌پور</last_name_fa>
	<suffix_fa></suffix_fa>
	<email></email>
	<code></code>
	<orcid></orcid>
	<coreauthor>No</coreauthor>
	<affiliation>Department of Ophthalmology, Rasoul Hospital, Faculty of Medicine, Tehran University of Medical Sciences, Tehran, Iran</affiliation>
	<affiliation_fa>دانشکده پزشکی، بیمارستان حضرت رسول اکرم ،دانشگاه علوم پزشکی تهران، تهران، ایران.</affiliation_fa>
	 </author>


</author_list>


	</article>
</articleset>
</journal>
