Tehran University Medical Journal
مجله دانشکده پزشکی، دانشگاه علوم پزشکی تهران
Tehran Univ Med J
Medical Sciences
http://tumj.tums.ac.ir
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1683-1764
1735-7322
10.18869/acadpub.tumj
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jalali
1390
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gregorian
2011
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ارتباط نمرهدهی جنسینی با ریسک بیماریهای قلبی و عروقی در بیماران با شاخصهای آنژیوگرافی
The relationship of Gensini score with the cardiovascular risk of patients with indication of angiography
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<p dir="rtl" style="text-align: justify direction: rtl unicode-bidi: embed" class="MsoNormal"><strong><span style="font-size: 10pt">زمینه و هدف</span></strong><span style="font-size: 10pt">:</span><span style="font-size: 10pt"> </span><span style="font-size: 10pt">شدت یافتههای
آنژیوگرافی در بیماری عروق کرونری در سیر پیشرفت و پیش</span><span style="font-size: 10pt"></span><span style="font-size: 10pt">آگهی بیماری مهم است و
امروزه معیار </span><span style="font-size: 7pt">G</span><span style="font-size: 8pt">ensini</span><span style="font-size: 10pt"> به طور وسیعی برای مشخص کردن بیماریهای قلبی و عروقی استفاده میشود.
با توجه به شیوع بالای بیماریهای قلبی و عروقی توجه به گزارش یافتههای
آنژیوگرافی میتواند در تشخیص شدت بیماریهای عروقی کرونر نقش مهمی داشته باشد. هدف
این مطالعه ارزیابی همراهی نمرهدهی جنسینی با ریسک فاکتورهای قلبی در بیمارانی که
مورد آنژیوگرافی عروق کرونر قرار میگیرند میباشد. <br></span></p><p dir="rtl" style="text-align: justify direction: rtl unicode-bidi: embed" class="MsoNormal"><span style="font-size: 10pt"></span><strong><span style="font-size: 10pt">روش
بررسی: </span></strong><span style="font-size: 10pt">این مطالعه به شکل مقطعی و به شکل گذشتهنگر طراحی شد. نمونهگیری به
روش آسان، شامل 495 بیمار از مراجعه کنندگان به بخش آنژیوگرافی بیمارستان شریعتی
از شهریور 88 تا شهریور 89 بود که دارای معیار ورود به مطالعه، داشتن اندیکاسیون
لازم برای آنژیوگرافی عروق کرونر بود. اطلاعات بیماران وارد پرسشنامه که شامل نام
و سن و سابقه وجود دیابت فشارخون </span><span style="font-size: 7pt">LDL, HDL</span><span style="font-size: 10pt">، لیپوپروتیین بالا بود ثبت شد.</span><span style="font-size: 11pt"> <br></span></p><p dir="rtl" style="text-align: justify direction: rtl unicode-bidi: embed" class="MsoNormal"><span style="font-size: 11pt"></span><strong><span style="font-size: 10pt">یافتهها:</span></strong><span style="font-size: 10pt"> </span><span style="font-size: 10pt">جمعیت شامل 249 مرد با میانگین سن 3/10</span><span style="font-size: 8pt">±</span><span style="font-size: 10pt">1/58 سال بود که
همراهی مثبت بین نمره بالای </span><span style="font-size: 7pt">G</span><span style="font-size: 8pt">ensini</span><span style="font-size: 10pt"> و دیابت، استعمال سیگار، </span><span style="font-size: 7pt">HDL</span><span style="font-size: 10pt"> <span lang="AR-SA">پایین و
سن و جنس دیده شد. از مجموع 495 بیمار 249 نفر (3/50) درصد مرد و 245 نفر (5/49)
درصد زن بودند. میانگین سن 341/10</span></span><span style="font-size: 8pt">±</span><span style="font-size: 10pt">10/58 بود که دامنه آن از (86–26)
سال بود. میانگین </span><span style="font-size: 7pt">TG</span><span style="font-size: 10pt"> 70</span><span style="font-size: 8pt">±</span><span style="font-size: 10pt">08/136
بود که دامنه آن از (564–123)</span><span style="font-size: 8pt"> </span><span style="font-size: 8pt">mg/dl</span><span style="font-size: 10pt"> بود. میانگین </span><span style="font-size: 7pt">HDL</span><span style="font-size: 10pt"> 13</span><span style="font-size: 8pt">±</span><span style="font-size: 10pt">22/50
بود که دامنه آن از (109–23) </span><span style="font-size: 8pt">mg/dl</span><span style="font-size: 10pt"> بود. میانگین </span><span style="font-size: 7pt">LDL</span><span style="font-size: 10pt"> 31</span><span style="font-size: 8pt">±</span><span style="font-size: 10pt">06/80
بود که دامنه آن از (189–113) </span><span style="font-size: 8pt">mg/dl</span><span style="font-size: 10pt"> بود.</span><span style="font-size: 10pt"><br></span></p><p dir="rtl" style="text-align: justify direction: rtl unicode-bidi: embed" class="MsoNormal"><span style="font-size: 10pt"> </span><strong><span style="font-size: 10pt">نتیجهگیری:</span><em><span style="font-size: 10pt"> </span></em></strong><span style="font-size: 10pt">در
بیمارانی که مورد آنژیوگرافی عروق کرونر قرار می</span><span style="font-size: 10pt"></span><span style="font-size: 10pt">گیرند معیار نمرهدهی
جنسینی ارزش قابل قبولی در همراهی با ریسک فاکتورهای قلبی دارد.</span><strong><em></em></strong></p>
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<!--stripped--> <strong>Background</strong><strong>:</strong> This study was designed to explore the contribution of risk factors for
coronary artery disease (CAD) in patients with
indication for coronary angiography. Coronary angiography is defined as the
radiographic visualization of the coronary vessels after injection of radio
opaque contrast media. Despite the recognition of risk factors for
CAD, the association between related risk factors and angiographic
findings remains controversial. The aim of the present study was to explore the
association between Gensini scores and major cardiovascular risk factors in
patients with indications for coronary angiography. <br><strong>Methods</strong><strong>:</strong> We retrospectively enrolled 495 patients who had
been hospitalized at Dr. Shariati Hospital during September 2009
to September 2010 and had undergone
coronary angiography. The patients were evaluated for the severity of coronary
lesions on the angiogram by Gensini scoring system. The patients were also
evaluated for the presence or absence of DM,
hypertension, family history of cardiac diseases, low HDL,
hyperlipoproteinemia, hypertriglyceridemia and cigarette smoking. Statistical
analysis wad done to find any relationship between Gensini scores and cardiovascular
risk factors.<br><strong>Results</strong><strong>:</strong> The study population consisted of 249
men (50.3%) and 245
woman (49.5%) with a mean age of 58.1±10.3
years. A positive correlation
was found between age (P=0.04), sex (P=0.008),
HDL (P=0.04) smoking (P=0.0001)
and diabetes (P<0.013) with Gensini scores.<br><strong>Conclusion:</strong> <a name="OLE_LINK8"></a><a name="OLE_LINK7">In
patients with indications of angiography, Gensini scores provide valuable
prognostic information on cardiovascular risk </a>factors. Age, sex, HDL, smoking
and diabetes <a name="OLE_LINK9">are related to the severity of coronary
lesions on the angiogram</a>s.</p>
نمرهدهی جنسینی،ریسک بیماریهای قلبی و عروقی،آنژیوگرافی عروق کرونر
Angiography,cardiovascular,coronary arteries,Gensini score,risk factors
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392
http://tumj.tums.ac.ir/browse.php?a_code=A-10-25-226&slc_lang=fa&sid=1
Mohagheghi
A
عباس
محققی