<?xml version="1.0" encoding="utf-8"?>
<journal>
<title>Tehran University Medical Journal</title>
<title_fa>مجله دانشکده پزشکی، دانشگاه علوم پزشکی تهران</title_fa>
<short_title>Tehran Univ Med J</short_title>
<subject>Medical Sciences</subject>
<web_url>http://tumj.tums.ac.ir</web_url>
<journal_hbi_system_id>1</journal_hbi_system_id>
<journal_hbi_system_user>admin</journal_hbi_system_user>
<journal_id_issn>1683-1764</journal_id_issn>
<journal_id_issn_online>1735-7322</journal_id_issn_online>
<journal_id_pii></journal_id_pii>
<journal_id_doi>10.18869/acadpub.tumj</journal_id_doi>
<journal_id_iranmedex></journal_id_iranmedex>
<journal_id_magiran></journal_id_magiran>
<journal_id_sid>000</journal_id_sid>
<journal_id_nlai>000</journal_id_nlai>
<journal_id_science>000</journal_id_science>
<language>fa</language>
<pubdate>
	<type>jalali</type>
	<year>1389</year>
	<month>11</month>
	<day>1</day>
</pubdate>
<pubdate>
	<type>gregorian</type>
	<year>2011</year>
	<month>2</month>
	<day>1</day>
</pubdate>
<volume>68</volume>
<number>11</number>
<publish_type>online</publish_type>
<publish_edition>1</publish_edition>
<article_type>fulltext</article_type>
<articleset>
	<article>


	<language>fa</language>
	<article_id_doi></article_id_doi>
	<title_fa>ارتباط نتایج تست متاکولین با علایم تنفسی: بررسی 146 بیمار</title_fa>
	<title>The association between methacholine challenge test and respiratory symptoms: a study on 146 patients</title>
	<subject_fa></subject_fa>
	<subject></subject>
	<content_type_fa></content_type_fa>
	<content_type></content_type>
	<abstract_fa>&lt;p&gt;&lt;!--stripped--&gt; &lt;o:OfficeDocumentSettings&gt; &lt;o:TargetScreenSize&gt;800x600&lt;/o:TargetScreenSize&gt; &lt;/o:OfficeDocumentSettings&gt; &lt;!--stripped--&gt;&lt;!--stripped--&gt; &lt;!--stripped--&gt; &lt;w:View&gt;Normal&lt;/w:View&gt; &lt;w:Zoom&gt;0&lt;/w:Zoom&gt; &lt;w:TrackMoves /&gt; &lt;w:TrackFormatting /&gt; &lt;w:PunctuationKerning /&gt; &lt;w:ValidateAgainstSchemas /&gt; &lt;w:SaveIfXMLInvalid&gt;false&lt;/w:SaveIfXMLInvalid&gt; &lt;w:IgnoreMixedContent&gt;false&lt;/w:IgnoreMixedContent&gt; &lt;w:AlwaysShowPlaceholderText&gt;false&lt;/w:AlwaysShowPlaceholderText&gt; &lt;w:DoNotPromoteQF /&gt; &lt;w:LidThemeOther&gt;EN-US&lt;/w:LidThemeOther&gt; &lt;w:LidThemeAsian&gt;X-NONE&lt;/w:LidThemeAsian&gt; &lt;w:LidThemeComplexScript&gt;AR-SA&lt;/w:LidThemeComplexScript&gt; &lt;w:Compatibility&gt; &lt;w:BreakWrappedTables /&gt; &lt;w:SnapToGridInCell /&gt; &lt;w:WrapTextWithPunct /&gt; &lt;w:UseAsianBreakRules /&gt; &lt;w:DontGrowAutofit /&gt; &lt;w:SplitPgBreakAndParaMark /&gt; &lt;w:EnableOpenTypeKerning /&gt; &lt;w:DontFlipMirrorIndents /&gt; &lt;w:OverrideTableStyleHps /&gt; &lt;/w:Compatibility&gt; &lt;w:BrowserLevel&gt;MicrosoftInternetExplorer4&lt;/w:BrowserLevel&gt; &lt;m:mathPr&gt; &lt;m:mathFont m:val=&quot;Cambria Math&quot; &gt; &lt;m:brkBin m:val=&quot;before&quot; &gt; &lt;m:brkBinSub m:val=&quot;--&quot; &gt; &lt;m:smallFrac m:val=&quot;off&quot; &gt; &lt;m:dispDef /&gt; &lt;m:lMargin m:val=&quot;0&quot; &gt; &lt;m:rMargin m:val=&quot;0&quot; &gt; &lt;m:defJc m:val=&quot;centerGroup&quot; &gt; &lt;m:wrapIndent m:val=&quot;1440&quot; &gt; &lt;m:intLim m:val=&quot;subSup&quot; &gt; &lt;m:naryLim m:val=&quot;undOvr&quot; &gt; &lt;/m:mathPr&gt;&lt;/w:WordDocument&gt; &lt;!--stripped--&gt;&lt;!--stripped--&gt; &lt;w:LatentStyles DefLockedState=&quot;false&quot; DefUnhideWhenUsed=&quot;true&quot;


  DefSemiHidden=&quot;true&quot; DefQFormat=&quot;false&quot; DefPriority=&quot;99&quot;


  LatentStyleCount=&quot;267&quot;&gt; &lt;w:LsdException Locked=&quot;false&quot; Priority=&quot;0&quot; SemiHidden=&quot;false&quot;


   UnhideWhenUsed=&quot;false&quot; QFormat=&quot;true&quot; Name=&quot;Normal&quot; &gt; &lt;w:LsdException Locked=&quot;false&quot; Priority=&quot;9&quot; SemiHidden=&quot;false&quot;


   UnhideWhenUsed=&quot;false&quot; QFormat=&quot;true&quot; Name=&quot;heading 1&quot; &gt; &lt;w:LsdException Locked=&quot;false&quot; Priority=&quot;9&quot; QFormat=&quot;true&quot; Name=&quot;heading 2&quot; &gt; &lt;w:LsdException Locked=&quot;false&quot; Priority=&quot;9&quot; QFormat=&quot;true&quot; Name=&quot;heading 3&quot; &gt; &lt;w:LsdException Locked=&quot;false&quot; Priority=&quot;9&quot; QFormat=&quot;true&quot; Name=&quot;heading 4&quot; &gt; &lt;w:LsdException Locked=&quot;false&quot; Priority=&quot;9&quot; QFormat=&quot;true&quot; Name=&quot;heading 5&quot; &gt; &lt;w:LsdException Locked=&quot;false&quot; Priority=&quot;9&quot; QFormat=&quot;true&quot; Name=&quot;heading 6&quot; &gt; &lt;w:LsdException Locked=&quot;false&quot; Priority=&quot;9&quot; QFormat=&quot;true&quot; Name=&quot;heading 7&quot; &gt; &lt;w:LsdException Locked=&quot;false&quot; Priority=&quot;9&quot; QFormat=&quot;true&quot; Name=&quot;heading 8&quot; &gt; &lt;w:LsdException Locked=&quot;false&quot; Priority=&quot;9&quot; QFormat=&quot;true&quot; Name=&quot;heading 9&quot; &gt; &lt;w:LsdException Locked=&quot;false&quot; Priority=&quot;39&quot; Name=&quot;toc 1&quot; &gt; &lt;w:LsdException Locked=&quot;false&quot; Priority=&quot;39&quot; Name=&quot;toc 2&quot; &gt; &lt;w:LsdException Locked=&quot;false&quot; Priority=&quot;39&quot; Name=&quot;toc 3&quot; &gt; &lt;w:LsdException Locked=&quot;false&quot; Priority=&quot;39&quot; Name=&quot;toc 4&quot; &gt; &lt;w:LsdException Locked=&quot;false&quot; Priority=&quot;39&quot; Name=&quot;toc 5&quot; &gt; &lt;w:LsdException Locked=&quot;false&quot; Priority=&quot;39&quot; Name=&quot;toc 6&quot; &gt; &lt;w:LsdException Locked=&quot;false&quot; Priority=&quot;39&quot; Name=&quot;toc 7&quot; &gt; &lt;w:LsdException Locked=&quot;false&quot; Priority=&quot;39&quot; Name=&quot;toc 8&quot; &gt; &lt;w:LsdException Locked=&quot;false&quot; Priority=&quot;39&quot; Name=&quot;toc 9&quot; &gt; &lt;w:LsdException Locked=&quot;false&quot; Priority=&quot;35&quot; QFormat=&quot;true&quot; Name=&quot;caption&quot; &gt; &lt;w:LsdException Locked=&quot;false&quot; Priority=&quot;10&quot; SemiHidden=&quot;false&quot;


   UnhideWhenUsed=&quot;false&quot; QFormat=&quot;true&quot; Name=&quot;Title&quot; &gt; &lt;w:LsdException Locked=&quot;false&quot; Priority=&quot;0&quot; Name=&quot;Default Paragraph Font&quot; &gt; &lt;w:LsdException Locked=&quot;false&quot; Priority=&quot;11&quot; SemiHidden=&quot;false&quot;


   UnhideWhenUsed=&quot;false&quot; QFormat=&quot;true&quot; Name=&quot;Subtitle&quot; &gt; &lt;w:LsdException Locked=&quot;false&quot; Priority=&quot;22&quot; SemiHidden=&quot;false&quot;


   UnhideWhenUsed=&quot;false&quot; QFormat=&quot;true&quot; Name=&quot;Strong&quot; &gt; &lt;w:LsdException Locked=&quot;false&quot; Priority=&quot;20&quot; SemiHidden=&quot;false&quot;


   UnhideWhenUsed=&quot;false&quot; QFormat=&quot;true&quot; Name=&quot;Emphasis&quot; &gt; &lt;w:LsdException Locked=&quot;false&quot; Priority=&quot;59&quot; SemiHidden=&quot;false&quot;


   UnhideWhenUsed=&quot;false&quot; Name=&quot;Table Grid&quot; &gt; &lt;w:LsdException Locked=&quot;false&quot; UnhideWhenUsed=&quot;false&quot; Name=&quot;Placeholder Text&quot; &gt; &lt;w:LsdException Locked=&quot;false&quot; Priority=&quot;1&quot; SemiHidden=&quot;false&quot;


   UnhideWhenUsed=&quot;false&quot; QFormat=&quot;true&quot; Name=&quot;No Spacing&quot; &gt; &lt;w:LsdException Locked=&quot;false&quot; Priority=&quot;60&quot; SemiHidden=&quot;false&quot;


   UnhideWhenUsed=&quot;false&quot; Name=&quot;Light Shading&quot; &gt; &lt;w:LsdException Locked=&quot;false&quot; Priority=&quot;61&quot; SemiHidden=&quot;false&quot;


   UnhideWhenUsed=&quot;false&quot; Name=&quot;Light List&quot; &gt; &lt;w:LsdException Locked=&quot;false&quot; Priority=&quot;62&quot; SemiHidden=&quot;false&quot;


   UnhideWhenUsed=&quot;false&quot; Name=&quot;Light Grid&quot; &gt; &lt;w:LsdException Locked=&quot;false&quot; Priority=&quot;63&quot; SemiHidden=&quot;false&quot;


   UnhideWhenUsed=&quot;false&quot; Name=&quot;Medium Shading 1&quot; &gt; &lt;w:LsdException Locked=&quot;false&quot; Priority=&quot;64&quot; SemiHidden=&quot;false&quot;


   UnhideWhenUsed=&quot;false&quot; Name=&quot;Medium Shading 2&quot; &gt; &lt;w:LsdException Locked=&quot;false&quot; Priority=&quot;65&quot; SemiHidden=&quot;false&quot;


   UnhideWhenUsed=&quot;false&quot; Name=&quot;Medium List 1&quot; &gt; &lt;w:LsdException Locked=&quot;false&quot; Priority=&quot;66&quot; SemiHidden=&quot;false&quot;


   UnhideWhenUsed=&quot;false&quot; Name=&quot;Medium List 2&quot; &gt; &lt;w:LsdException Locked=&quot;false&quot; Priority=&quot;67&quot; SemiHidden=&quot;false&quot;


   UnhideWhenUsed=&quot;false&quot; Name=&quot;Medium Grid 1&quot; &gt; &lt;w:LsdException Locked=&quot;false&quot; Priority=&quot;68&quot; SemiHidden=&quot;false&quot;


   UnhideWhenUsed=&quot;false&quot; Name=&quot;Medium Grid 2&quot; &gt; &lt;w:LsdException Locked=&quot;false&quot; Priority=&quot;69&quot; SemiHidden=&quot;false&quot;


   UnhideWhenUsed=&quot;false&quot; Name=&quot;Medium Grid 3&quot; &gt; &lt;w:LsdException Locked=&quot;false&quot; Priority=&quot;70&quot; SemiHidden=&quot;false&quot;


   UnhideWhenUsed=&quot;false&quot; Name=&quot;Dark List&quot; &gt; &lt;w:LsdException Locked=&quot;false&quot; Priority=&quot;71&quot; SemiHidden=&quot;false&quot;


   UnhideWhenUsed=&quot;false&quot; Name=&quot;Colorful Shading&quot; &gt; &lt;w:LsdException Locked=&quot;false&quot; Priority=&quot;72&quot; SemiHidden=&quot;false&quot;


   UnhideWhenUsed=&quot;false&quot; Name=&quot;Colorful List&quot; &gt; &lt;w:LsdException Locked=&quot;false&quot; Priority=&quot;73&quot; SemiHidden=&quot;false&quot;


   UnhideWhenUsed=&quot;false&quot; Name=&quot;Colorful Grid&quot; &gt; &lt;w:LsdException Locked=&quot;false&quot; Priority=&quot;60&quot; SemiHidden=&quot;false&quot;


   UnhideWhenUsed=&quot;false&quot; Name=&quot;Light Shading Accent 1&quot; &gt; &lt;w:LsdException Locked=&quot;false&quot; Priority=&quot;61&quot; SemiHidden=&quot;false&quot;


   UnhideWhenUsed=&quot;false&quot; Name=&quot;Light List Accent 1&quot; &gt; &lt;w:LsdException Locked=&quot;false&quot; Priority=&quot;62&quot; SemiHidden=&quot;false&quot;


   UnhideWhenUsed=&quot;false&quot; Name=&quot;Light Grid Accent 1&quot; &gt; &lt;w:LsdException Locked=&quot;false&quot; Priority=&quot;63&quot; SemiHidden=&quot;false&quot;


   UnhideWhenUsed=&quot;false&quot; Name=&quot;Medium Shading 1 Accent 1&quot; &gt; &lt;w:LsdException Locked=&quot;false&quot; Priority=&quot;64&quot; SemiHidden=&quot;false&quot;


   UnhideWhenUsed=&quot;false&quot; Name=&quot;Medium Shading 2 Accent 1&quot; &gt; &lt;w:LsdException Locked=&quot;false&quot; Priority=&quot;65&quot; SemiHidden=&quot;false&quot;


   UnhideWhenUsed=&quot;false&quot; Name=&quot;Medium List 1 Accent 1&quot; &gt; &lt;w:LsdException Locked=&quot;false&quot; UnhideWhenUsed=&quot;false&quot; Name=&quot;Revision&quot; &gt; &lt;w:LsdException Locked=&quot;false&quot; Priority=&quot;34&quot; SemiHidden=&quot;false&quot;


   UnhideWhenUsed=&quot;false&quot; QFormat=&quot;true&quot; Name=&quot;List Paragraph&quot; &gt; &lt;w:LsdException Locked=&quot;false&quot; Priority=&quot;29&quot; SemiHidden=&quot;false&quot;


   UnhideWhenUsed=&quot;false&quot; QFormat=&quot;true&quot; Name=&quot;Quote&quot; &gt; &lt;w:LsdException Locked=&quot;false&quot; Priority=&quot;30&quot; SemiHidden=&quot;false&quot;


   UnhideWhenUsed=&quot;false&quot; QFormat=&quot;true&quot; Name=&quot;Intense Quote&quot; &gt; &lt;w:LsdException Locked=&quot;false&quot; Priority=&quot;66&quot; SemiHidden=&quot;false&quot;


   UnhideWhenUsed=&quot;false&quot; Name=&quot;Medium List 2 Accent 1&quot; &gt; &lt;w:LsdException Locked=&quot;false&quot; Priority=&quot;67&quot; SemiHidden=&quot;false&quot;


   UnhideWhenUsed=&quot;false&quot; Name=&quot;Medium Grid 1 Accent 1&quot; &gt; &lt;w:LsdException Locked=&quot;false&quot; Priority=&quot;68&quot; SemiHidden=&quot;false&quot;


   UnhideWhenUsed=&quot;false&quot; Name=&quot;Medium Grid 2 Accent 1&quot; &gt; &lt;w:LsdException Locked=&quot;false&quot; Priority=&quot;69&quot; SemiHidden=&quot;false&quot;


   UnhideWhenUsed=&quot;false&quot; Name=&quot;Medium Grid 3 Accent 1&quot; &gt; &lt;w:LsdException Locked=&quot;false&quot; Priority=&quot;70&quot; SemiHidden=&quot;false&quot;


   UnhideWhenUsed=&quot;false&quot; Name=&quot;Dark List Accent 1&quot; &gt; &lt;w:LsdException Locked=&quot;false&quot; Priority=&quot;71&quot; SemiHidden=&quot;false&quot;


   UnhideWhenUsed=&quot;false&quot; Name=&quot;Colorful Shading Accent 1&quot; &gt; &lt;w:LsdException Locked=&quot;false&quot; Priority=&quot;72&quot; SemiHidden=&quot;false&quot;


   UnhideWhenUsed=&quot;false&quot; Name=&quot;Colorful List Accent 1&quot; &gt; &lt;w:LsdException Locked=&quot;false&quot; Priority=&quot;73&quot; SemiHidden=&quot;false&quot;


   UnhideWhenUsed=&quot;false&quot; Name=&quot;Colorful Grid Accent 1&quot; &gt; &lt;w:LsdException Locked=&quot;false&quot; Priority=&quot;60&quot; SemiHidden=&quot;false&quot;


   UnhideWhenUsed=&quot;false&quot; Name=&quot;Light Shading Accent 2&quot; &gt; &lt;w:LsdException Locked=&quot;false&quot; Priority=&quot;61&quot; SemiHidden=&quot;false&quot;


   UnhideWhenUsed=&quot;false&quot; Name=&quot;Light List Accent 2&quot; &gt; &lt;w:LsdException Locked=&quot;false&quot; Priority=&quot;62&quot; SemiHidden=&quot;false&quot;


   UnhideWhenUsed=&quot;false&quot; Name=&quot;Light Grid Accent 2&quot; &gt; &lt;w:LsdException Locked=&quot;false&quot; Priority=&quot;63&quot; SemiHidden=&quot;false&quot;


   UnhideWhenUsed=&quot;false&quot; Name=&quot;Medium Shading 1 Accent 2&quot; &gt; &lt;w:LsdException Locked=&quot;false&quot; Priority=&quot;64&quot; SemiHidden=&quot;false&quot;


   UnhideWhenUsed=&quot;false&quot; Name=&quot;Medium Shading 2 Accent 2&quot; &gt; &lt;w:LsdException Locked=&quot;false&quot; Priority=&quot;65&quot; SemiHidden=&quot;false&quot;


   UnhideWhenUsed=&quot;false&quot; Name=&quot;Medium List 1 Accent 2&quot; &gt; &lt;w:LsdException Locked=&quot;false&quot; Priority=&quot;66&quot; SemiHidden=&quot;false&quot;


   UnhideWhenUsed=&quot;false&quot; Name=&quot;Medium List 2 Accent 2&quot; &gt; &lt;w:LsdException Locked=&quot;false&quot; Priority=&quot;67&quot; SemiHidden=&quot;false&quot;


   UnhideWhenUsed=&quot;false&quot; Name=&quot;Medium Grid 1 Accent 2&quot; &gt; &lt;w:LsdException Locked=&quot;false&quot; Priority=&quot;68&quot; SemiHidden=&quot;false&quot;


   UnhideWhenUsed=&quot;false&quot; Name=&quot;Medium Grid 2 Accent 2&quot; &gt; &lt;w:LsdException Locked=&quot;false&quot; Priority=&quot;69&quot; SemiHidden=&quot;false&quot;


   UnhideWhenUsed=&quot;false&quot; Name=&quot;Medium Grid 3 Accent 2&quot; &gt; &lt;w:LsdException Locked=&quot;false&quot; Priority=&quot;70&quot; SemiHidden=&quot;false&quot;


   UnhideWhenUsed=&quot;false&quot; Name=&quot;Dark List Accent 2&quot; &gt; &lt;w:LsdException Locked=&quot;false&quot; Priority=&quot;71&quot; SemiHidden=&quot;false&quot;


   UnhideWhenUsed=&quot;false&quot; Name=&quot;Colorful Shading Accent 2&quot; &gt; &lt;w:LsdException Locked=&quot;false&quot; Priority=&quot;72&quot; SemiHidden=&quot;false&quot;


   UnhideWhenUsed=&quot;false&quot; Name=&quot;Colorful List Accent 2&quot; &gt; &lt;w:LsdException Locked=&quot;false&quot; Priority=&quot;73&quot; SemiHidden=&quot;false&quot;


   UnhideWhenUsed=&quot;false&quot; Name=&quot;Colorful Grid Accent 2&quot; &gt; &lt;w:LsdException Locked=&quot;false&quot; Priority=&quot;60&quot; SemiHidden=&quot;false&quot;


   UnhideWhenUsed=&quot;false&quot; Name=&quot;Light Shading Accent 3&quot; &gt; &lt;w:LsdException Locked=&quot;false&quot; Priority=&quot;61&quot; SemiHidden=&quot;false&quot;


   UnhideWhenUsed=&quot;false&quot; Name=&quot;Light List Accent 3&quot; &gt; &lt;w:LsdException Locked=&quot;false&quot; Priority=&quot;62&quot; SemiHidden=&quot;false&quot;


   UnhideWhenUsed=&quot;false&quot; Name=&quot;Light Grid Accent 3&quot; &gt; &lt;w:LsdException Locked=&quot;false&quot; Priority=&quot;63&quot; SemiHidden=&quot;false&quot;


   UnhideWhenUsed=&quot;false&quot; Name=&quot;Medium Shading 1 Accent 3&quot; &gt; &lt;w:LsdException Locked=&quot;false&quot; Priority=&quot;64&quot; SemiHidden=&quot;false&quot;


   UnhideWhenUsed=&quot;false&quot; Name=&quot;Medium Shading 2 Accent 3&quot; &gt; &lt;w:LsdException Locked=&quot;false&quot; Priority=&quot;65&quot; SemiHidden=&quot;false&quot;


   UnhideWhenUsed=&quot;false&quot; Name=&quot;Medium List 1 Accent 3&quot; &gt; &lt;w:LsdException Locked=&quot;false&quot; Priority=&quot;66&quot; SemiHidden=&quot;false&quot;


   UnhideWhenUsed=&quot;false&quot; Name=&quot;Medium List 2 Accent 3&quot; &gt; &lt;w:LsdException Locked=&quot;false&quot; Priority=&quot;67&quot; SemiHidden=&quot;false&quot;


   UnhideWhenUsed=&quot;false&quot; Name=&quot;Medium Grid 1 Accent 3&quot; &gt; &lt;w:LsdException Locked=&quot;false&quot; Priority=&quot;68&quot; SemiHidden=&quot;false&quot;


   UnhideWhenUsed=&quot;false&quot; Name=&quot;Medium Grid 2 Accent 3&quot; &gt; &lt;w:LsdException Locked=&quot;false&quot; Priority=&quot;69&quot; SemiHidden=&quot;false&quot;


   UnhideWhenUsed=&quot;false&quot; Name=&quot;Medium Grid 3 Accent 3&quot; &gt; &lt;w:LsdException Locked=&quot;false&quot; Priority=&quot;70&quot; SemiHidden=&quot;false&quot;


   UnhideWhenUsed=&quot;false&quot; Name=&quot;Dark List Accent 3&quot; &gt; &lt;w:LsdException Locked=&quot;false&quot; Priority=&quot;71&quot; SemiHidden=&quot;false&quot;


   UnhideWhenUsed=&quot;false&quot; Name=&quot;Colorful Shading Accent 3&quot; &gt; &lt;w:LsdException Locked=&quot;false&quot; Priority=&quot;72&quot; SemiHidden=&quot;false&quot;


   UnhideWhenUsed=&quot;false&quot; Name=&quot;Colorful List Accent 3&quot; &gt; &lt;w:LsdException Locked=&quot;false&quot; Priority=&quot;73&quot; SemiHidden=&quot;false&quot;


   UnhideWhenUsed=&quot;false&quot; Name=&quot;Colorful Grid Accent 3&quot; &gt; &lt;w:LsdException Locked=&quot;false&quot; Priority=&quot;60&quot; SemiHidden=&quot;false&quot;


   UnhideWhenUsed=&quot;false&quot; Name=&quot;Light Shading Accent 4&quot; &gt; &lt;w:LsdException Locked=&quot;false&quot; Priority=&quot;61&quot; SemiHidden=&quot;false&quot;


   UnhideWhenUsed=&quot;false&quot; Name=&quot;Light List Accent 4&quot; &gt; &lt;w:LsdException Locked=&quot;false&quot; Priority=&quot;62&quot; SemiHidden=&quot;false&quot;


   UnhideWhenUsed=&quot;false&quot; Name=&quot;Light Grid Accent 4&quot; &gt; &lt;w:LsdException Locked=&quot;false&quot; Priority=&quot;63&quot; SemiHidden=&quot;false&quot;


   UnhideWhenUsed=&quot;false&quot; Name=&quot;Medium Shading 1 Accent 4&quot; &gt; &lt;w:LsdException Locked=&quot;false&quot; Priority=&quot;64&quot; SemiHidden=&quot;false&quot;


   UnhideWhenUsed=&quot;false&quot; Name=&quot;Medium Shading 2 Accent 4&quot; &gt; &lt;w:LsdException Locked=&quot;false&quot; Priority=&quot;65&quot; SemiHidden=&quot;false&quot;


   UnhideWhenUsed=&quot;false&quot; Name=&quot;Medium List 1 Accent 4&quot; &gt; &lt;w:LsdException Locked=&quot;false&quot; Priority=&quot;66&quot; SemiHidden=&quot;false&quot;


   UnhideWhenUsed=&quot;false&quot; Name=&quot;Medium List 2 Accent 4&quot; &gt; &lt;w:LsdException Locked=&quot;false&quot; Priority=&quot;67&quot; SemiHidden=&quot;false&quot;


   UnhideWhenUsed=&quot;false&quot; Name=&quot;Medium Grid 1 Accent 4&quot; &gt; &lt;w:LsdException Locked=&quot;false&quot; Priority=&quot;68&quot; SemiHidden=&quot;false&quot;


   UnhideWhenUsed=&quot;false&quot; Name=&quot;Medium Grid 2 Accent 4&quot; &gt; &lt;w:LsdException Locked=&quot;false&quot; Priority=&quot;69&quot; SemiHidden=&quot;false&quot;


   UnhideWhenUsed=&quot;false&quot; Name=&quot;Medium Grid 3 Accent 4&quot; &gt; &lt;w:LsdException Locked=&quot;false&quot; Priority=&quot;70&quot; SemiHidden=&quot;false&quot;


   UnhideWhenUsed=&quot;false&quot; Name=&quot;Dark List Accent 4&quot; &gt; &lt;w:LsdException Locked=&quot;false&quot; Priority=&quot;71&quot; SemiHidden=&quot;false&quot;


   UnhideWhenUsed=&quot;false&quot; Name=&quot;Colorful Shading Accent 4&quot; &gt; &lt;w:LsdException Locked=&quot;false&quot; Priority=&quot;72&quot; SemiHidden=&quot;false&quot;


   UnhideWhenUsed=&quot;false&quot; Name=&quot;Colorful List Accent 4&quot; &gt; &lt;w:LsdException Locked=&quot;false&quot; Priority=&quot;73&quot; SemiHidden=&quot;false&quot;


   UnhideWhenUsed=&quot;false&quot; Name=&quot;Colorful Grid Accent 4&quot; &gt; &lt;w:LsdException Locked=&quot;false&quot; Priority=&quot;60&quot; SemiHidden=&quot;false&quot;


   UnhideWhenUsed=&quot;false&quot; Name=&quot;Light Shading Accent 5&quot; &gt; &lt;w:LsdException Locked=&quot;false&quot; Priority=&quot;61&quot; SemiHidden=&quot;false&quot;


   UnhideWhenUsed=&quot;false&quot; Name=&quot;Light List Accent 5&quot; &gt; &lt;w:LsdException Locked=&quot;false&quot; Priority=&quot;62&quot; SemiHidden=&quot;false&quot;


   UnhideWhenUsed=&quot;false&quot; Name=&quot;Light Grid Accent 5&quot; &gt; &lt;w:LsdException Locked=&quot;false&quot; Priority=&quot;63&quot; SemiHidden=&quot;false&quot;


   UnhideWhenUsed=&quot;false&quot; Name=&quot;Medium Shading 1 Accent 5&quot; &gt; &lt;w:LsdException Locked=&quot;false&quot; Priority=&quot;64&quot; SemiHidden=&quot;false&quot;


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&lt;!--stripped--&gt; &lt;strong&gt;زمینه و
هدف: &lt;/strong&gt;آسم
(Asthma) یک بیماری تهدید‌کننده حیات است که می‌تواند با
اسپاسم و انسداد راه‌های هوایی سبب مرگ شود. جهت تشخیص آسم در کنار علایم بالینی
نظیر خس‌‌خس سینه، تنگی نفس حمله‌ای، سرفه مزمن و یا سرفه به‌دنبال تماس با هوای
سرد و یا به‌‌دنبال فعالیت وجود معیار اسپیرومتری نیز لازم می‌باشد. اما رابطه
نتایج تست متاکولین مثبت با علایم تنفسی مشخص نمی‌باشد. هدف این مقاله بررسی رابطه
بین نتایج تست متاکولین و با علایم تنفسی بیماران و آلرژی می‌باشد. &lt;strong&gt;&lt;/strong&gt;&lt;/p&gt;
&lt;p style=&quot;text-align: justify&quot; dir=&quot;rtl&quot;&gt;&lt;strong&gt;روش بررسی: &lt;/strong&gt;در مطالعه ما 146 بیمار با علایم
تنفسی در یک مطالعه مقطعی تحت بررسی قرار گرفتند. جمعیت تحت مطالعه عبارت بودند از
بیماران دارای علایم بیماری‌های تنفسی نظیر سرفه مزمن، خس‌خس سینه، تنگی‌نفس که در
معاینه بالینی نرمال بوده و اسپیرومتری پایه نرمال داشتند و با توجه به‌نتایج تست
متاکولین به دو گروه تست مثبت و منفی تقسیم شدند و رابطه نتایج تست با علایم تنفسی
بررسی شد.&lt;strong&gt; &lt;/strong&gt;&lt;/p&gt;
&lt;p style=&quot;text-align: justify&quot; dir=&quot;rtl&quot;&gt;&lt;strong&gt;&lt;/strong&gt;&lt;strong&gt;یافته‌ها:&lt;/strong&gt; تعداد 146 بیمار وارد
مطالعه شدند که 59 بیمار (4/40%) مونث و 87 بیمار (6/59%) مذکر بودند. میانگین سن
بیماران تحت مطالعه 8/13±8/33 سال بوده است. 61
بیمار (8/41) تست مثبت داشتند و بین سابقه آلرژی و خس‌خس سینه و سن با نتایج تست
ارتباط معنی‌داری وجود داشت. بین سایر علایم بالینی با نتایج تست متاکولین ارتباط
معنی‌داری دیده نشد.&lt;strong&gt; &lt;/strong&gt;&lt;/p&gt;
&lt;p style=&quot;text-align: justify&quot; dir=&quot;rtl&quot;&gt;&lt;strong&gt;نتیجه‌گیری: &lt;/strong&gt;تست
متاکولین بهترین روش برای رد تشخیص آسم در افرادی است که تست عملکرد ریه نرمال
دارند اما با توجه به علایم بالینی نمی‌توان آسم را به‌صورت قطعی رد کرد اما در
افراد زیر 30 سالی که با خس‌خس سینه و سابقه آلرژی مراجعه می‌کنند احتمال مثبت شدن
تست زیاد است.&lt;/p&gt;</abstract_fa>
	<abstract>&lt;p style=&quot;text-align: justify&quot;&gt;&lt;strong&gt;Background: &lt;/strong&gt;Asthma is a life-threatening disease that can cause death due to bronchospasm. In addition to clinical symptoms such as wheezing, acute paroxysmal dyspnea, chronic cough after exposure to cold air or cough after exercise, spirometry is also necessary for the diagnosis of asthma. The association between respiratory symptoms and a positive methacholine challenge test (MCT) is still controversial. The aim of this study was to determine the association between methacholine test results and respiratory symptoms and allergy.&lt;br&gt;&lt;strong&gt;&lt;/strong&gt;&lt;/p&gt;
&lt;p style=&quot;text-align: justify&quot;&gt;&lt;strong&gt;Methods:&lt;/strong&gt; One hundred and forty-six patients with respiratory symptoms and normal baseline pulmonary function tests were enrolled in this cross-sectional study. The participants were divided into two groups according to their positive or negative response to MCT. The association between MCT and the clinical symptoms and allergy was later evaluated statistically.&lt;br&gt;&lt;strong&gt;&lt;/strong&gt;&lt;/p&gt;
&lt;p style=&quot;text-align: justify&quot;&gt;&lt;strong&gt;Results: &lt;/strong&gt;Out of 146 participants of the study 59 (40.4%) were female and 87 (59.6%) were male. The mean age of the participants was 33.8±13.8 years. Sixty-one patients (41.8%) had positive results for the test. There was an association between a history of allergy, wheezing and age with positive MCT results. The other clinical signs had no association with the test.&lt;br&gt;&lt;strong&gt;&lt;/strong&gt;&lt;/p&gt;
&lt;p style=&quot;text-align: justify&quot;&gt;&lt;strong&gt;Conclusion: &lt;/strong&gt;Methacholine challenge test is the best diagnostic test for ruling out asthma in patients with normal pulmonary function tests in whom we cannot definitely rule out asthma based solely on clinical symptoms. Nevertheless, in adults with a history of allergy, wheezing and also in patients below 30, the probability for a positive MCT is high.&lt;/p&gt;</abstract>
	<keyword_fa>تست متاکولین,آسم,علایم تنفسی</keyword_fa>
	<keyword>Asthma,methacholine challenge test,respiratory symptoms,spirometry</keyword>
	<start_page>662</start_page>
	<end_page>667</end_page>
	<web_url>http://tumj.tums.ac.ir/browse.php?a_code=A-10-25-294&amp;slc_lang=fa&amp;sid=1</web_url>


<author_list>
	<author>
	<first_name>Paknejad</first_name>
	<middle_name></middle_name>
	<last_name>O</last_name>
	<suffix></suffix>
	<first_name_fa>ام‌البنین</first_name_fa>
	<middle_name_fa></middle_name_fa>
	<last_name_fa>پاک‌نژاد</last_name_fa>
	<suffix_fa></suffix_fa>
	<email></email>
	<code></code>
	<orcid></orcid>
	<coreauthor>No</coreauthor>
	<affiliation></affiliation>
	<affiliation_fa>گروه ریه، بیمارستان شریعتی  دانشگاه  علوم پزشکی  تهران</affiliation_fa>
	 </author>


	<author>
	<first_name>Hojjati</first_name>
	<middle_name></middle_name>
	<last_name>SA</last_name>
	<suffix></suffix>
	<first_name_fa>سیده امینه</first_name_fa>
	<middle_name_fa></middle_name_fa>
	<last_name_fa>حجتی</last_name_fa>
	<suffix_fa></suffix_fa>
	<email>amineh_hojati@yahoo.com</email>
	<code></code>
	<orcid></orcid>
	<coreauthor>Yes
</coreauthor>
	<affiliation></affiliation>
	<affiliation_fa>گروه داخلی، بیمارستان شریعتی   دانشگاه  علوم پزشکی  تهران</affiliation_fa>
	 </author>


	<author>
	<first_name>Pazoki</first_name>
	<middle_name></middle_name>
	<last_name>M</last_name>
	<suffix></suffix>
	<first_name_fa>مرضیه</first_name_fa>
	<middle_name_fa></middle_name_fa>
	<last_name_fa>پازوکی</last_name_fa>
	<suffix_fa></suffix_fa>
	<email></email>
	<code></code>
	<orcid></orcid>
	<coreauthor>No</coreauthor>
	<affiliation></affiliation>
	<affiliation_fa>گروه ریه بیمارستان سینا    دانشگاه  علوم پزشکی  تهران</affiliation_fa>
	 </author>


</author_list>


	</article>
</articleset>
</journal>
