fa اثر بیماری کبد چرب غیرالکلی بر روی نمایه‌های داپلر عروق کبدی <p dir="rtl" style="text-align: justify"><!--stripped--> Normal 0 false false false EN-GB X-NONE AR-SA MicrosoftInternetExplorer4 <!--stripped--><!--stripped--> <!--stripped--> <!--stripped--> <style> /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Table Normal" mso-tstyle-rowband-size:0 mso-tstyle-colband-size:0 mso-style-noshow:yes mso-style-priority:99 mso-style-qformat:yes mso-style-parent:"" mso-padding-alt:0cm 5.4pt 0cm 5.4pt mso-para-margin:0cm mso-para-margin-bottom:.0001pt mso-pagination:widow-orphan font-size:11.0pt font-family:"Calibri","sans-serif" mso-ascii-font-family:Calibri mso-ascii-theme-font:minor-latin mso-fareast-font-family:"Times New Roman" mso-fareast-theme-font:minor-fareast mso-hansi-font-family:Calibri mso-hansi-theme-font:minor-latin mso-bidi-font-family:Arial mso-bidi-theme-font:minor-bidi} </style> <!--stripped--> <strong>زمینه و هدف</strong>: سونوگرافی داپلر اخیرا به عنوان یک روش تشخیصی مهم برای بررسی غیرتهاجمی عروق کبدی و برخی بیماری‌های پارانشیم کبد مطرح شده است. یافته‌های جدید نشان داده است که انفیلتراسیون چربی می‌تواند نمایه‌های داپلر شریان و ورید کبدی را تحت تاثیر قرار دهد. مطالعه زیر جهت ارزیابی اثر انفیلتراسیون چربی بر اندکس مقاومت شریان کبدی و فرم امواج ورید کبدی طراحی شده است. <strong><br></strong></p><p dir="rtl" style="text-align: justify"><strong>روش بررسی</strong>: تعداد 60 بیمار با درجات مختلف کبد چرب در بیوپسی کبد و تعداد 20 نفر بدون آثار انفیلتراسیون چربی در سونوگرافی در این مطالعه تحت بررسی توسط سونوگرافی داپلر استاندارد قرار گرفتند. امواج ورید کبدی به سه گروه تقسیم شدند: امواج تری‌فازیک طبیعی، امواج بای‌فازیک بدون جریان بازگشتی و امواج مونوفازیک. اندکس مقاومت شریان کبدی به صورت متوسط سه اندازه‌گیری متوالی محاسبه شد. <br></p><p dir="rtl" style="text-align: justify"><strong>یافته‌ها</strong>: میانگین شاخص توده بدنی (Body mass index) در افراد نرمال و مبتلا به کبد چرب  در محدوده ²kg/m44- 20 قرار داشت. امواج غیرطبیعی ورید کبدی (بای‌فازیک و مونوفازیک) در بیماران مبتلا به NAFLD 12 نفر بای‌فازیک و 17 نفر مونوفازیک در مقایسه با افراد نرمال شیوع بیشتری دارد. اندکس مقاومت شریان کبدی نیز در بیماران مبتلا به NAFLD به طور معنی‌داری پایین تر از افراد نرمال است.</p><p dir="rtl" style="text-align: justify"> <strong>نتیجه‌گیری</strong>: شیوع امواج غیرطبیعی ورید کبدی در بیماران مبتلا به NAFLD در مقایسه با افراد طبیعی بالاتر است و این افراد اندکس مقاومت شریان کبدی پایین‌تری دارند.</p> <p style="text-align: justify"><!--stripped--> Normal 0 false false false EN-GB X-NONE AR-SA MicrosoftInternetExplorer4 <!--stripped--><!--stripped--> <!--stripped--><!--stripped--> !mso]> <ob<illegal tag>ject classid="clsid:38481807-CA0E-42D2-BF39-B33AF135CC4D" id=ieooui> </object> <style> st1":*{behavior:url(#ieooui) } </style> <!--stripped--> <!--stripped--> <style> /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Table Normal" mso-tstyle-rowband-size:0 mso-tstyle-colband-size:0 mso-style-noshow:yes mso-style-priority:99 mso-style-qformat:yes mso-style-parent:"" mso-padding-alt:0cm 5.4pt 0cm 5.4pt mso-para-margin:0cm mso-para-margin-bottom:.0001pt mso-pagination:widow-orphan font-size:11.0pt font-family:"Calibri","sans-serif" mso-ascii-font-family:Calibri mso-ascii-theme-font:minor-latin mso-fareast-font-family:"Times New Roman" mso-fareast-theme-font:minor-fareast mso-hansi-font-family:Calibri mso-hansi-theme-font:minor-latin mso-bidi-font-family:Arial mso-bidi-theme-font:minor-bidi} </style> <!--stripped--> <strong>Background</strong><strong>:</strong> Duplex Doppler ultrasonography (US) has newly suggested, being an important diagnostic technique in the non-invasive evaluation of hepatic vasculature and some hepatic parenchymal diseases. New findings suggest that diffuse fatty infiltration of liver can alter normal hepatic vein and artery doppler indices. The following study has been performed to evaluate the effect of fatty infiltration on hepatic artery resistance index and hepatic vein waveform patterns.<br><strong>Methods</strong><strong>:</strong> Sixty patients with various degrees of fatty infiltration on liver biopsy and twenty normal subjects without any sign of hepatic fat infiltration in ultrasonography examined using standard colour and spectral doppler sonography. The waveforms of Hepatic Vein were classified into three groups: regular triphasic waveform, biphasic waveform without a reverse flow, and monophasic or flat waveform. The hepatic artery resistance index was calculated as the mean of three different measurements.<br><strong>Results</strong><strong>:</strong> The mean BMI in Nonalcoholic fatty liver disease group and normal subjects was 26.9(SD=3.3) and 22.4(SD=1.7) Kg/m², respectively with a range of 22 up to 44 Kg/m². Abnormal Hepatic Vein waveforms (biphasic and monophasic) were found more frequently in doppler sonography (p<0.001) in patients with Nonalcoholic fatty liver disease (12 biphasic and 17 monophasic) compared to normal subjects. Hepatic artery resistance index was significantly lower in Nonalcoholic fatty liver disease patients [0.7(SD=0.1)] compared to normal ones [0.8(SD=0.0)] (p<0.001).<br><strong>Conclusions:</strong> The incidence of abnormal hepatic vein waveforms is significantly higher in patients with fatty infiltration compared to those who had no abnormality in liver ultrasonography and these patients had a significant lower hepatic artery resistance index.<!--stripped--> supportFields]> ADDIN EN.CITE  ADDIN EN.CITE.DATA <![if gte mso 9]><xm<illegal tag>l> 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<!--stripped--><!--stripped--> supportFields]><!--stripped--></p> کبد چرب غیر الکلی،داپلر،ورید کبدی،شریان کبدی Nonalcoholic fatty liver disease,doppler,Hepatic vein,Hepatic artery 112 117 http://tumj.tums.ac.ir/browse.php?a_code=A-10-25-481&slc_lang=fa&sid=1 Mohammadinia AR امیررضا محمدی‌نیا No Bakhtavar K خدیجه بخت‌آور No Ebrahimi-Daryani N ناصر ابراهیمی دریانی Yes Habibollahi P پیمان حبیب‌الهی No Keramati MR محمدرضا کرامتی No Fereshtehnejad SM سیدمحمد فرشته نژاد No