Volume 61, Issue 6 (15 2003)                   Tehran Univ Med J 2003, 61(6): 475-483 | Back to browse issues page

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Shadkhast M, Tootian Z, Fazelipour S, Bokaii S. Study Of Morphological Changes Of Uterine Horn Of Surri Mouse Depended To Morphine Before Puberty And DuringPuberty. Tehran Univ Med J. 2003; 61 (6) :475-483
URL: http://tumj.tums.ac.ir/article-1-1156-en.html
Abstract:   (4396 Views)
Morphine is the most important alkaloid of opium family which is found as much as ten percent in opium, and is in two types the sulfate morphine and the hydrochloride morphine.
Materials and Methods: In this study morphological changes of uterus of surri mice due to oral consumption of sulfate morphine were studied. It was shown that, female surri mice following gradually increasing of morphine to water (0.1 and 0.01) mg/ml were depended to morphine. Female surri mice were classified in two age groups before puberty and depended to morphine during puberty. Each age group took morphine for 21 days. After finishing the period, the mice anesthetizing were weighted, then were anesthetizing and uterus was studied the length, width and apparent features.
Results&ConcIusion: In this study it was distinguished that length and width of uterine horn, between experimental and control groups, were significant (P< 0.01). Morphological changes such as anemia, the thinness and fragitidily walls of uterus and filiformity of uterine horns were observed.


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