Mandibular osteosarcoma presenting as a peripheral 
tumoral mass: a case report

Abdolsamadi , Hamidreza; Mahmoudvand, Pardies; Pourgholi Takrami , Zahra; Alipour, Elahe

Volume 83, Issue 3 (June 2025) Tehran Univ Med J 2025, 83(3): 226-232 | Back to browse issues page

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Abdolsamadi H, Mahmoudvand P, Pourgholi Takrami Z, Alipour E. Mandibular osteosarcoma presenting as a peripheral tumoral mass: a case report. Tehran Univ Med J 2025; 83 (3) :226-232
URL: http://tumj.tums.ac.ir/article-1-13552-en.html

Mandibular osteosarcoma presenting as a peripheral tumoral mass: a case report

Hamidreza Abdolsamadi¹

, Pardies Mahmoudvand ^*²

, Zahra Pourgholi Takrami²

, Elahe Alipour²

1- Department of Oral Diseases, Dental Research Center, School of Dentistry, Hamadan University of Medical Sciences, Hamadan, Iran.
2- Department of Oral Diseases, Faculty of Dentistry, Hamedan University of Medical Sciences, Hamedan, Iran.

Abstract: (542 Views)

Background: Although osteosarcoma in the head and neck region is relatively rare accounting for 2.1% of all malignant oral and maxillofacial tumors it is nevertheless regarded as the most common primary malignant bone tumor in children and young adults. In the craniofacial skeleton its overall occurrence remains uncommon, and that rarity contributes to diagnostic difficulty and occasional delay. The neoplasm is recognized simultaneously for its infrequency and its malignant character, and these features together can obscure recognition when early symptoms are muted or resemble more benign oral conditions. Because presentations may be subtle, careful clinical attention to patient-reported sensations and visible mucosal or submucosal changes is advisable. Early complaints may initially involve tingling paresthesia or awareness of a focal oral mass. Vigilance matters in everyday oral and maxillofacial practice.
Case Presentation: The patient was a 38-year-old married man from Asadabad County, Hamedan Province, who presented to the Department of Oral and Maxillofacial Diseases at the School of Dentistry, Hamedan, during February March 2025. He reported a tingling, electric-shock like sensation together with a lesion on the floor of the mouth. The persistence of the sensation and the presence of a visible lesion prompted evaluation in a specialized academic clinic. The demographic context, the anatomic location in the floor of the mouth, and the clear time frame are central features of the presentation. The chief complaint centered on the peculiar sensation and the discernible lesion, which together motivated clinical assessment in an oral and maxillofacial setting.
Conclusion: This report highlights the importance of considering mandibular osteosarcoma in the differential diagnosis of peripheral tumoral lesions. Reporting such cases can improve understanding of unusual clinical presentations and assist in more accurate clinical decision-making. The central message is unchanged: clinicians should include mandibular osteosarcoma among diagnostic possibilities when encountering peripheral lesions so that evaluation proceeds thoughtfully.

Keywords: malignant bone tumor, mandible, osteosarcoma, peripheral tumoral lesion.

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Type of Study: Case Report |