Volume 78, Issue 8 (November 2020)
Tehran Univ Med J 2020, 78(8): 537-546 |
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Molatefi R, Ahadi A, Salehzadeh H, Safarzadeh E, Abbasi H. The prevalence of respiratory allergens in patients with asthma and allergic rhinitis in Ardabil province. Tehran Univ Med J 2020; 78 (8) :537-546
URL: http://tumj.tums.ac.ir/article-1-10788-en.html
URL: http://tumj.tums.ac.ir/article-1-10788-en.html
1- Department of Pediatrics, Bo-Ali Children's Hospital, School of Medicine, Ardabil University of Medical Sciences, Ardabil, Iran.
2- Department of Microbiology & Immunology, School of Medicine, Ardabil University of Medical Sciences, Ardabil, Iran.
3- Student of Medicine, School of Medicine, Ardabil University of Medical Sciences, Ardabil, Iran.
2- Department of Microbiology & Immunology, School of Medicine, Ardabil University of Medical Sciences, Ardabil, Iran.
3- Student of Medicine, School of Medicine, Ardabil University of Medical Sciences, Ardabil, Iran.
Abstract: (1522 Views)
Background: Because of geographic variation and regional types of allergens, it is recommended that allergists identify common allergens in their area of activity. In the present study, the prevalence of respiratory allergens in patients with asthma and allergic rhinitis was investigated.
Methods: This study is descriptive and retrospective. The required data of this study were extracted from the records of 661 patients who were referred to the Asthma and Allergy Clinic of Ardabil University of Medical Sciences (Ardabil province, Northwest of Iran) from April 2016 to March 2017. After confirmation of allergic asthma or rhinitis by the asthma and allergy specialist, these patients were subjected to a prick test with allergen extracts. In the group of grasses the extract of nine grasses, in trees the extract of 11 Tree mix, in weeds the extract of Common weed mix, in animal allergens the three extracts of Standard cat, Dog epithelia, Cockroach mix, in weeds the Mite mix and in fungi, three extracts of Mold mix1, Alternaria and Aspergillus mix were used. All the data were analyzed using SPSS software, version 25.
Methods: This study is descriptive and retrospective. The required data of this study were extracted from the records of 661 patients who were referred to the Asthma and Allergy Clinic of Ardabil University of Medical Sciences (Ardabil province, Northwest of Iran) from April 2016 to March 2017. After confirmation of allergic asthma or rhinitis by the asthma and allergy specialist, these patients were subjected to a prick test with allergen extracts. In the group of grasses the extract of nine grasses, in trees the extract of 11 Tree mix, in weeds the extract of Common weed mix, in animal allergens the three extracts of Standard cat, Dog epithelia, Cockroach mix, in weeds the Mite mix and in fungi, three extracts of Mold mix1, Alternaria and Aspergillus mix were used. All the data were analyzed using SPSS software, version 25.
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Results: According to results, of the 661 patients who were studied, 462 ones had positive and 273 had significant prick test results. The grasses group with 293 positive (44.3%) and weeds group with 259 positive results (39.2%) were more common than the other categories. Among the significant positive tests, these two categories with 161 and 142 significant positive tests were indicated as the most common allergens. Respiratory allergens were also more common in patients with a family history of allergies in weeds and trees categories, but there was no significant difference in sensitization pattern according to the history of tonsillectomy.
Conclusion: Patients in Ardabil with allergic rhinitis and asthma were more sensitized to weeds and grass mixtures. It is recommended to provide preventive recommendations to allergic patients and the development of localized skin testing packages and additional studies should be conducted focusing on these two categories of allergens. |
Type of Study: Original Article |
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