The evaluation of clinical symptoms and underlying 
factors in infected patients with Covid-19

Jaafarabadi, Mina; Bagheri, Maryam; Shariat, Mamak; Raeisie, Khadijeh; Ranjbar, Athareh; Ghafoori, Faezeh; Haghollahi, Fedyeh

Volume 78, Issue 10 (January 2021) Tehran Univ Med J 2021, 78(10): 668-677 | Back to browse issues page

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Jaafarabadi M, Bagheri M, Shariat M, Raeisie K, Ranjbar A, Ghafoori F et al . The evaluation of clinical symptoms and underlying factors in infected patients with Covid-19. Tehran Univ Med J 2021; 78 (10) :668-677
URL: http://tumj.tums.ac.ir/article-1-10932-en.html

The evaluation of clinical symptoms and underlying factors in infected patients with Covid-19

Mina Jaafarabadi ^*

¹, Maryam Bagheri²

, Mamak Shariat³

, Khadijeh Raeisie⁴

, Athareh Ranjbar⁵

, Faezeh Ghafoori⁶

, Fedyeh Haghollahi⁷

1- Department of Obstetrics & Gynecology, Vali-Asr Reproductive Health Research Center, Tehran University of Medical Sciences, Tehran, Iran.
2- Department of Midwifery and Reproductive Health, School of Nursing and Midwifery, Tehran University of Medical Sciences, Tehran, Iran.
3- Maternal, Fetal & Neonatal Research Center, Family Health Institute, Tehran University of Medical Sciences, Tehran, Iran.
4- Department of Nursing, Imam Khomeini Hospital Complex, School of Nursing, Tehran University of Medical Sciences, Tehran, Iran.
5- Department of Nursing, Imam Khomeini Complex, School of Nursing, Tehran University of Medical Sciences, Tehran, Iran.
6- Department of Population, Family and School Health, Deputy of Health, Ministry of Health and Medical Education, Tehran, Iran.
7- Vali -Asr Reproductive Health Research Center, Tehran University of Medical Sciences, Tehran, Iran.

Abstract: (3256 Views)

Background: The pandemic of Covid-19 is spreading around the world. Extensive research is needed to focus on identifying the underlying causes of the disease. This study aimed to investigate the clinical and etiological symptoms of the Covid-19.
Methods: This descriptive-analytical study, conducted on 510 infected patients in the infectious disease clinic of Imam Khomeini Hospital in Tehran from March 2019 to June 2020 for A period of Four months during the first wave of Covid-19 pandemic. The method of selecting patients was continuous and was divided into two groups of 179 inpatients and 331 outpatients based on lung scan and clinical symptoms. Demographic information, clinical signs, and risk factors were collected through a questionnaire and the data were statistically analyzed.

Results: Symptoms such as fever, chills and cough were reported in the majority of patients in both groups, to such an extent that they were present in 176 (52%) of outpatients and in 101 (59%) of inpatients. The mean hemoglobin measured in hospitalized patients was lower, P=0.001). Vitamin D3 supplementation was reported in 30% of outpatients and in 16.5% of hospitalized patients (P=0.001). This means that vitamin D3 consumption is higher in the outpatient group.
The results showed that Chronic diseases such as hypertension was 4.9 times more likely (OR=4.9, 95% CI2. 433-10.25, P=0.0001) and anemia with 22 times more likely (OR=22.905, 95% CI9. 355-56.083, P=0.000) to be effective in the severity of the disease. It seems Vitamin D3 intake has a supportive effect on reducing the severity of the disease and decreases the risk of the disease getting worse.

Conclusion: Fever, chills and cough were important symptoms in identifying infected patients with Covid-19. According to the results of the present study and the findings of other studies, the supportive effect of vitamin D3 in reducing the severity of infectious diseases should be considered. Clinical trials with appropriate sample size are recommended to investigate the functional role of this vitamin in Reducing the severity of viral diseases of the respiratory tract.