Volume 82, Issue 1 (April 2024)                   Tehran Univ Med J 2024, 82(1): 46-53 | Back to browse issues page

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Najafi F, Amiri Delui M, Moradi M, Sarkhosh P, Rezaian Z, Sharifymood F et al . Comparison of the effects of Althaea officinalis and eucalyptus nebulizers on the severity of cough in patients with Covid-19: Clinical trial. Tehran Univ Med J 2024; 82 (1) :46-53
URL: http://tumj.tums.ac.ir/article-1-12997-en.html
1- Department of Nursing School of Nursing, Gonabad University of Medical Sciences, Gonabad, Iran.
2- Nursing Research Center, Gonabad University of Medical Sciences, Gonabad, Iran.
3- Social Development and Health Promotion Research Center, Gonabad University of Medical Sciences, Gonabad, Iran.
4- Infectious Diseases Research Center ,Gonabad university of medical scinces, Gonabad, Iran.
5- Nursing Research Center, Gonabad University of Medical Sciences, Gonabad, Iran. , kameli1366@yahoo.com
Abstract:   (149 Views)
Background: one of the most common and important complications of COVID-19 is cough. The present study was designed with the aim of comparing the effect of althaea officinalis and eucalyptus nebulizer on the severity of cough in COVID-19 patients.
Methods: in this randomized clinical trial, from January 2022 to June 2022, 36 patients with COVID-19 were selected and randomly divided into three groups. Next, the severity of cough was recorded two hours before the intervention based on the visual analogue (VAS) in both groups until the patient was admitted to the hospital, then, one cc aqueous extract of althaea officinalis with five cc Normal Saline for the althaea officinalis group and four cc aqueous extract eucalyptus whit five cc Normal Saline for the eucalyptus group, were nebulized once a day for 15 minutes. Two hours after the intervention, the intensity of cough was again recorded in two groups. This intervention continued until the hospitalization of the patients. No intervention was done for the control group. The data was analyzed with Spss software at a significance level of less than 0.05.
Results: In this study before the intervention, there was no statistically significant difference between the three groups in terms of cough intensity (p>0.05), but after the intervention on the second and third days, there was a statistically significant difference between the three groups in terms of cough intensity. The rate of reduction in cough severity in althaea officinalis group was higher than the other two groups (p<0.05).  Also, the results of Friedman's test indicated that althaea officinalis and eucalyptus nebulizers incense improved the severity of cough in patients over time.
Conclusion: the use of althaea officinalis and eucalyptus nebulizer improved the severity of cough in patients with COVID-19, but althaea officinalis nebulizer had a greater effect on cough severity compared to eucalyptus. It is suggested to use althaea officinalis nebulizer as well as eucalyptus as a treatment method along with other treatment methods.
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