Evaluation of the results of renal biopsy performed on diabetic patients referred to Imam Khomeini and Golestan Hospitals of 
Ahwaz, southwest Iran

Ahmadi Halili , Shahla; Soltani, Zahra; Hesam, Saeed; Khombi Shooshtari , Maryam

Volume 82, Issue 5 (August 2024) Tehran Univ Med J 2024, 82(5): 406-412 | Back to browse issues page

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Ahmadi Halili S, Soltani Z, Hesam S, Khombi Shooshtari M. Evaluation of the results of renal biopsy performed on diabetic patients referred to Imam Khomeini and Golestan Hospitals of Ahwaz, southwest Iran. Tehran Univ Med J 2024; 82 (5) :406-412
URL: http://tumj.tums.ac.ir/article-1-13172-en.html

Evaluation of the results of renal biopsy performed on diabetic patients referred to Imam Khomeini and Golestan Hospitals of Ahwaz, southwest Iran

Shahla Ahmadi Halili¹

, Zahra Soltani²

, Saeed Hesam³

, Maryam Khombi Shooshtari ^*

⁴

1- Department of Internal Medicine, Chronic Renal Failure Research Center, School of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
2- Department of Internal Medicine, School of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
3- Department of Biostatistics and Epidemiology, School of Health, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
4- Chronic Renal Failure Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran. , shooshtari91@gmail.com

Abstract: (15 Views)

Background: Diabetic nephropathy is one of the most important complications of diabetes worldwide. In diabetic patients, although renal biopsies performed with less frequency, it is important because these patients may have glomerular disorders other than diabetic nephropathy. Therefore, in this study, we investigated the results of renal biopsies performed on diabetic patients referred to diabetic clinics in Imam Khomeini and Golestan hospitals in Ahvaz, southwest Iran.
Methods: In this descriptive-cross-sectional study, information related to biopsy samples from 67 patients recognize with diabetes who underwent renal biopsy from August 2103 to September 2018, collected and recorded retrospectively. The presence of diabetic nephropathy and other renal diseases was confirmed by pathological evaluation of all renal biopsy specimens. Then, the data were analyzed by using SPSS 20 software.

Results: The results of this study presented that diabetic nephropathy (67.2%), diabetic nephropathy along with acute tubulointerstitial nephritis (7.5%), acute tubulointerstitial nephritis (6%) and membrane glomerulonephritis (6%) were the most frequent diagnosis in diabetic patients with renal disorder. Furthermore, in the described cases, class IV (47.9%), III (35.4%) and II (12.5%) and I (4.2%) were the most common classes of nephropathy, respectively. Interestingly, there was no significant association between age, sex, proteinuria and hematuria with the frequency of nephropathy in the patient who underwent renal biopsy. Also, in this study, the frequency of class I and II nephropathy was 100% in patients older than 50 years, while 64.7% of class III was in patients under 50 years of age, which was also statistically significant (P=0.018). On the other hand, in the studied patients, there were not significant different between the frequency of diabetic nephropathy class and proteinuria, azotemia, and hematuria (P>0.05).
Conclusion: According to the obtained results, to reduce the risk of complications and costs, it seems crucial to be more wary in pick out diabetic patients for renal biopsy and to enhance the threshold of renal biopsy in diabetic patients as much as possible.

Keywords: diabetes, nephropathy, renal biopsy.

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Type of Study: Original Article |