Volume 64, Issue 11 (7 2006)
Tehran Univ Med J 2006, 64(11): 44-50 |
Back to browse issues page
Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:
Gharagozlou M, Montazeran M, Foroozanfar M, Khalili S. The effect of influenza vaccination in the prevention of exacerbation of children asthma. Tehran Univ Med J 2006; 64 (11) :44-50
URL: http://tumj.tums.ac.ir/article-1-872-en.html
URL: http://tumj.tums.ac.ir/article-1-872-en.html
Abstract: (5643 Views)
Background: Influenza epidemies which occur mosthly in cold seasons could be a risk factor for developing exacerbations and acute attacks of asthma. Although influenza vaccination is recommended for the asthmatic patients, there is a lack of sufficient clinical evidence that this annual vaccination prevents asthma exacerbation in children.
Methods: Prospective clinical trial study of 201 children with asthma, where 79 did, and 122 did not receive the influenza vaccine, was done. The two groups were compared with respect to use of bronchodilators, systemic corticosteroids, emergency department (ED) visits and hospitalizations for asthma. In multi variable analysis, adjustment was made for baseline asthma severity and demographic variables.
Results: After adjusting for other variables, the vaccinated group had a significant decreased in exacerbations frequency and duration. Also the frequency of used bronchodilators and the absence days of daycare center or school were lower in the vaccinated group (P<0.05). There was no significant difference between the two groups in relation to used systemic corticosteroids and ED or hospital admissions (P>005).
Conclusion: This study showed that influenza vaccination may be effective in prevention of some asthma exacerbation aspects.
Methods: Prospective clinical trial study of 201 children with asthma, where 79 did, and 122 did not receive the influenza vaccine, was done. The two groups were compared with respect to use of bronchodilators, systemic corticosteroids, emergency department (ED) visits and hospitalizations for asthma. In multi variable analysis, adjustment was made for baseline asthma severity and demographic variables.
Results: After adjusting for other variables, the vaccinated group had a significant decreased in exacerbations frequency and duration. Also the frequency of used bronchodilators and the absence days of daycare center or school were lower in the vaccinated group (P<0.05). There was no significant difference between the two groups in relation to used systemic corticosteroids and ED or hospital admissions (P>005).
Conclusion: This study showed that influenza vaccination may be effective in prevention of some asthma exacerbation aspects.
| Rights and permissions | |
 |
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License. |
